Comparing reduced stent strategy with conventional stent treatment for heart attack patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of a reduced stent strategy using drug-coated balloons (DCB) compared to the conventional approach of using drug-eluting stents (DES) in patients experiencing ST-segment myocardial infarction (STEMI). Patients will be randomly assigned to either the DCB-based strategy or the DES-based strategy after successful guidewire crossing and restoration of blood flow. The study seeks to determine which method provides better outcomes for patients undergoing percutaneous coronary intervention (PCI).

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Patients presenting with STEMI and indication to undergo pPCI.

Exclusion Criteria:

* Life expectancy \<1 year due 1 to non-cardiac disease.
* Inability to provide informed consent.
* Cardiogenic shock.
* Left ventricular ejection fraction \<15%.
* Left main disease.
* Stent thrombosis
* Patients with prior bypass graft lesions requiring PCI (culprit or non culprit lesions).
* Patients with chronic total occlusions.
* Untreatable coronary disease.
* Non-identified culprit lesion.
* Known allergy to aspirin, ticagrelor, prasugrel, clopidogrel, paclitaxel or sirolimus.

Where it's running

• Hospital Universitario Juan Ramón Jiménez
  Huelva, Huelva, Spain Recruiting
• Hospital Universitario Y Politecnico La Fe
  Valencia, Valencia, Spain Recruiting
• Complejo Hospitalario Universitario de A Coruña
  A Coruña, Spain Recruiting
• Hospital Universitario de Burgos
  Burgos, Spain Recruiting
• Consorcio Hospitalario Provincial de Castellon
  Castelló, Spain Recruiting
• Hospital Universitario Reina Sofía de Córdoba
  Córdoba, Spain Recruiting

Study contacts

• Principal investigator: Jorge Sanz Sánchez, PI — Hospital Universitario La Fe
• Study coordinator: Naiara García Lamas
• Email: naiara@pinvestiga.com
• Phone: 634213101

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.