Comparing recovery methods after laparoscopic sleeve gastrectomy

Quality of Recovery in Laparoscopic Sleeve Gastrectomy Using Dexmedetomidine Infusion Versus Laparoscopic TAP Block in Combination With Paragastric Neural Block

PHASE2; PHASE3 · Alexandria University · NCT06970626

This study is testing which recovery method works better for people with obesity after laparoscopic sleeve gastrectomy by comparing two different pain management techniques.

Quick facts

PhasePHASE2; PHASE3
Study typeInterventional
Enrollment60 (estimated)
Ages20 Years to 60 Years
SexAll
SponsorAlexandria University (other)
Locations1 site (Alexandria)
Trial IDNCT06970626 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to determine which recovery method is more effective for patients undergoing laparoscopic sleeve gastrectomy: a combination of dexmedetomidine infusion and paragastric neural block or a combination of laparoscopic TAP block and paragastric neural block. The study will evaluate recovery by measuring opioid consumption, hemodynamic stability, pain scores, quality of postoperative recovery, and incidence of nausea or vomiting. It involves patients with a BMI of 35-50 kg/m2 and ASA physical status II-III, assessing their recovery outcomes post-surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with a BMI between 35 and 50 kg/m2 and classified as ASA physical status II-III.

Not a fit: Patients with significant hepatic, renal, neuromuscular, or cardiac impairments, extreme obesity (BMI > 50 kg/m2), or those currently on opioid medication may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved recovery protocols for patients undergoing laparoscopic sleeve gastrectomy, potentially reducing pain and opioid use.

How similar studies have performed: Other studies have shown promising results with similar approaches in enhancing recovery after surgical procedures, suggesting potential for success in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. American Society of Anesthesiologists (ASA) physical status II- III
2. BMI 35- 50 kg/m2

Exclusion Criteria:

1. Significant hepatic, renal, neuromuscular, or cardiac impairments
2. Extreme obesity (BMI \> 50 kg/m2)
3. Patients on current opioid medication
4. Allergies to dexmedetomidine or bupivacaine

Where this trial is running

Alexandria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Laparoscopic Sleeve Gastrectomy, dexmedetomidine, Paragastric Neural Block, Laparoscopic TAP

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.