Comparing quality of life in thyroid cancer patients after different surgeries
Comparison of Quality of Life Between Patients with Early Differentiated Thyroid Cancer Undergoing Minimally Invasive and Open Surgery: a Prospective Cohort Study
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · NCT06037174
This study looks at how different types of thyroid cancer surgery affect the quality of life, voice, and scarring for patients with early-stage thyroid cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 230 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (other) |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT06037174 on ClinicalTrials.gov |
What this trial studies
This observational study follows patients with early differentiated thyroid cancer who undergo either traditional open surgery or minimally invasive procedures. The aim is to assess the impact of these surgical approaches on patients' quality of life, voice, and scarring through regular follow-ups and standardized questionnaires. By comparing outcomes, the study seeks to provide evidence that minimally invasive surgery may offer better aesthetic results and overall quality of life improvements compared to conventional methods.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 70 with biopsy-confirmed differentiated thyroid carcinoma at early stages.
Not a fit: Patients with aggressive thyroid cancer types or those with a history of thyroid surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical options for thyroid cancer patients, enhancing their quality of life post-surgery.
How similar studies have performed: Previous studies have shown promising results for minimally invasive surgical techniques in various cancers, suggesting potential success for this approach in thyroid cancer as well.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years and \< 70 years; * Biopsy or surgical pathology indicated differentiated thyroid carcinoma (papillary thyroid carcinoma, follicular carcinoma); * stage T1\~T3a, N0\~N1a, M0; * Ability to read and write Chinese; * Willingness to follow up. Exclusion Criteria: * Age \< 18 years old or ≥70 years old; * Biopsy or surgical pathology indicated medullary carcinoma or anaplastic thyroid carcinoma; * Aggressive histology: tall cell, columnar cell, hobnail variant, etc. * Mixed with medullary carcinoma or anaplastic thyroid carcinoma; * High risk of recurrence (according to ATA guideline); * Lateral cervical lymph node metastasis or distant metastasis; * Suffer from other malignant tumors; * History of thyroid surgery or cervical lymph node dissection; * Cognition or behavior impairment.
Where this trial is running
Guangzhou, Guangdong
- Sun Yat-sen Memorial Hopsital — Guangzhou, Guangdong, China (RECRUITING)
Study contacts
- Study coordinator: Xiaoming Huang, Professor
- Email: hxming@mail.sysu.edu.cn
- Phone: 13602808820
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Thyroid Cancer, thyroid cancer, quality of life, minimally invasive, surgery