Comparing pulse oximeters in newborns

Pulse Oximetry Performance Comparison in Newborns

Medtronic - MITG · NCT06637917

This study is testing two different pulse oximeters to see which one gives more accurate readings of heart rate and oxygen levels in newborns right after birth.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages29 Weeks and up
SexAll
SponsorMedtronic - MITG (industry)
Locations3 sites (Los Angeles, California and 2 other locations)
Trial IDNCT06637917 on ClinicalTrials.gov

What this trial studies

This observational study aims to directly compare the performance of two different pulse oximeters in measuring pulse rate and oxygen saturation in newborns. The study will involve the use of the OxySoftN™ Neonatal-Adult SpO2 Sensor with the N600X Nellcor™ Patient Monitoring System and the LNCS® NEO SpO2 Sensor with the RAD-97™ Pulse CO-Oximeter. Newborns who meet the eligibility criteria will be monitored in the delivery room to assess the effectiveness of these devices in real-time. The goal is to determine which device provides more accurate readings for this vulnerable population.

Who should consider this trial

Good fit: Ideal candidates for this study are newborns who are at least 29 weeks gestational age and can accommodate multiple sensors.

Not a fit: Patients with existing health conditions that may interfere with accurate oximetry measurements, such as major congenital anomalies or limb anomalies, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of oxygen saturation monitoring in newborns, leading to better clinical outcomes.

How similar studies have performed: While this study focuses on a specific comparison of pulse oximeters, similar studies have shown varying degrees of success in improving monitoring techniques in neonatal care.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parent or legal guardian is willing and able to provide informed consent prior to any study procedures being performed.
* Subject is expected to be able to participate for the duration of the evaluation in the delivery room. In most instances, the length of the study will not exceed the anticipated duration of ECG monitoring.
* Subject is ≥ 29 weeks gestational age.
* Subject can accommodate multiple sensors.

Exclusion Criteria:

* Subjects that have an existing health condition, in which the investigator determines that safe or accurate oximetry measures may not be obtained at the areas where the PO sensor could be placed. For example, major congenital anomalies, limb anomalies or anyone with abrasions or surface lesions on the contact areas would be excluded.
* Any subject whose treatment or condition would be compromised if they were to participate in this study and any patient whose use of a pulse oximeter and sensor would present a potential for serious risk to health, safety, or welfare.
* Currently participating in any other study expected to confound study results in the opinion of the investigator.

Where this trial is running

Los Angeles, California and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Newborn, Birth, Preterm

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.