Comparing Pregabalin and Lacosamide for Pain Relief in Shingles Patients
Official title: Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic Neuralgia
Run by CMH Kharian Medical College · NCT06969417 · Data updated 2026-11-12
This study is testing whether Pregabalin or Lacosamide works better to relieve pain in adults aged 18 to 50 who have post-herpetic neuralgia after shingles.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | CMH Kharian Medical College Government |
| Locations | 1 site (Kharan, Punjab Province) |
| Status | Recruiting |
| Started | April 10, 2025 |
| Main results expected | July 31, 2025 |
| Study ends | September 30, 2025 |
| Registry record updated | May 14, 2025 |
| Trial ID | NCT06969417 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 50 diagnosed with herpes zoster and experiencing post-herpetic neuralgia.
✕Probably not a fit
Patients who are already taking painkillers for post-herpetic neuralgia or have other systemic illnesses may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of two medications, Pregabalin and Lacosamide, in treating post-herpetic neuralgia (PHN), a painful condition that can occur after shingles. The study involves patients aged 18 to 50 who have been diagnosed with herpes zoster and are experiencing PHN. Participants will receive either Pregabalin or Lacosamide to determine which medication provides better pain relief. The trial aims to address the often debilitating pain associated with PHN, which can significantly impact daily life and well-being.
Why it matters
Potential benefit: If successful, this study could provide effective pain management options for patients suffering from post-herpetic neuralgia.
How similar studies have gone: Other studies have explored the efficacy of Pregabalin and Lacosamide for neuropathic pain, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed cases of herpes zoster suffering from postherpetic neuralgia * Ages: 18 to 50 * Both male and female Exclusion Criteria: * Lack of consent * Patient already taking pain killers for post herpetic neuralgia * Patients suffering from other systemic illness
Where it's running
-
CMH Kharian Medical College
Kharan, Punjab Province, Pakistan Recruiting
Study contacts
- Study coordinator: Mushayada Irshad, MBBS, MPhil Pharmacology
- Email: mishy2360@gmail.com
- Phone: +92537532239
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.