Clinical trial Recruiting at 1 site Interventional Ages 18 to 50

Comparing Pregabalin and Lacosamide for Pain Relief in Shingles Patients

Official title: Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic Neuralgia

Run by CMH Kharian Medical College · NCT06969417 · Data updated 2026-11-12

This study is testing whether Pregabalin or Lacosamide works better to relieve pain in adults aged 18 to 50 who have post-herpetic neuralgia after shingles.

More Herpes Zoster (HZ) trials

Quick facts

Study typeInterventional
Ages18 Years to 50 Years
SexAll
Enrollment50 (estimated)
SponsorCMH Kharian Medical College
Government
Locations1 site (Kharan, Punjab Province)
StatusRecruiting
StartedApril 10, 2025
Main results expectedJuly 31, 2025
Study endsSeptember 30, 2025
Registry record updatedMay 14, 2025
Trial IDNCT06969417 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 to 50 diagnosed with herpes zoster and experiencing post-herpetic neuralgia.

Probably not a fit

Patients who are already taking painkillers for post-herpetic neuralgia or have other systemic illnesses may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of two medications, Pregabalin and Lacosamide, in treating post-herpetic neuralgia (PHN), a painful condition that can occur after shingles. The study involves patients aged 18 to 50 who have been diagnosed with herpes zoster and are experiencing PHN. Participants will receive either Pregabalin or Lacosamide to determine which medication provides better pain relief. The trial aims to address the often debilitating pain associated with PHN, which can significantly impact daily life and well-being.

Why it matters

Potential benefit: If successful, this study could provide effective pain management options for patients suffering from post-herpetic neuralgia.

How similar studies have gone: Other studies have explored the efficacy of Pregabalin and Lacosamide for neuropathic pain, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed cases of herpes zoster suffering from postherpetic neuralgia
* Ages: 18 to 50
* Both male and female

Exclusion Criteria:

* Lack of consent
* Patient already taking pain killers for post herpetic neuralgia
* Patients suffering from other systemic illness

Where it's running

  • CMH Kharian Medical College
    Kharan, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.