Comparing Povidone-iodine and Saline for Preventing Infections in Colorectal Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial aims to evaluate the effectiveness of povidone-iodine versus saline solution in reducing surgical site infections (SSI) in patients undergoing colorectal resections. Participants will be randomly assigned to receive either povidone-iodine or saline for irrigation of their surgical incisions during the procedure. The study will take place at a large university hospital in Southern Brazil, where standard care routines will remain unchanged. The outcomes of both groups will be compared to determine which irrigation method is more effective in preventing SSI.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients older than 18 years of age diagnosed with benign or malignant colorectal diseases undergoing elective open or video-assisted colectomy or proctectomy (resection) at the Hospital de Clinicas de Porto Alegre - Division of Coloproctology.

Exclusion Criteria:

* age under 18;
* surgery classified as dirty;
* urgent/emergency surgery;
* patients undergoing multi-visceral resections (pelvic exenteration or partial resection of any adjacent organ);
* known allergy to iodine.

Where it's running

• Hospital de Clinicas de Porto Alegre
  Porto Alegre, Rio Grande do Sul, Brazil Recruiting

Study contacts

• Principal investigator: Daniel C Damin, PhD — Hospital de Clinicas de Porto Alegre
• Study coordinator: Daniel C Damin, PhD
• Email: damin@terra.com.br
• Phone: +5551996020442

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.