Comparing Plurogel to standard dressings for burn injuries
A Between Patient, Pilot Randomized Controlled Study of Plurogel® Compared to Standard Topical Dressing in Burn Injuries
This study is testing whether Plurogel works better than regular dressings for treating partial thickness burns by helping patients heal faster and reducing the need for surgery.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Manitoba Academic / other |
| Locations | 1 site (Winnipeg, Manitoba) |
| Trial ID | NCT05000983 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of Plurogel compared to standard antibiotic topical dressings in patients with partial thickness burns. The study aims to determine if Plurogel can reduce the need for surgical debridement and improve healing outcomes. Participants will be monitored for their recovery process, including pain management and healing time. The trial is designed to gather data on the safety and efficacy of Plurogel in treating burn injuries.
Who should consider this trial
Good fit: Ideal candidates are individuals with partial thickness burns on the face or unilateral limbs requiring hospitalization.
Not a fit: Patients with total burn surface area greater than 30% or full thickness burns will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved healing and reduced surgical interventions for patients with burn injuries.
How similar studies have performed: Other studies have explored similar adjuncts for burn treatment, but definitive improvements have not been established in randomized controlled trials.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Persons with partial thickness face burns or unilateral limb burn injuries requiring admission. Exclusion Criteria: * Total burn surface area (TBSA) \>30%. * Burn depth full thickness or deeper on initial assessment. * Prior excision at another healthcare centre. * Patients with pre-existing malnutrition * Electrical, chemical or other unusual burn etiologies
Where this trial is running
Winnipeg, Manitoba
- University of Manitoba — Winnipeg, Manitoba, Canada (Recruiting)
Study contacts
- Study coordinator: Justin Gawaziuk, MSc
- Email: jgawaziuk@hsc.mb.ca
- Phone: 2047878682
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.