Comparing Platelet-Rich Plasma Injection and Hydrodissection for Carpal Tunnel Syndrome
A Prospective Comparative Study on the Efficacy of Ultrasound-Guided Platelet-Rich Plasma Injection Versus Hydrodissection in the Treatment of Carpal Tunnel Syndrome
This study is testing whether a new injection treatment or a different technique can help people with Carpal Tunnel Syndrome feel better and improve their hand function.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 64 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Mansoura University Academic / other |
| Locations | 1 site (Mansoura) |
| Trial ID | NCT06368505 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of Ultrasound-Guided Platelet-Rich Plasma (PRP) Injection versus Hydrodissection in treating Carpal Tunnel Syndrome. Participants will be randomly assigned to one of the two treatment groups and will undergo assessments before and after the intervention at 1 and 3 months. The study will measure symptom reduction and functional improvement, as well as the safety profiles of both methods. Ultrasound will be used to guide the injections and assess the condition of the median nerve.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with Carpal Tunnel Syndrome experiencing symptoms for at least three months.
Not a fit: Patients who have had previous carpal tunnel surgery or corticosteroid injections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for patients suffering from Carpal Tunnel Syndrome.
How similar studies have performed: Other studies have shown promising results with similar ultrasound-guided interventions, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed clinically as carpal tunnel syndrome with at least 3 months of symptoms and confirmed electro-physiologically as carpal tunnel syndrome Exclusion Criteria: * Onset of carpal tunnel syndrome during pregnancy * Co-existence of brachial plexopathy or thoracic outlet syndrome by clinical examination * Previous carpal tunnel decompressive surgery or corticosteroid injection in carpal tunnel * Patients with infection or local edema at the site of injection.
Where this trial is running
Mansoura
- Mansoura University — Mansoura, Egypt (Recruiting)
Study contacts
- Study coordinator: osama elshafei, MD, PHD
- Email: osama_elshafei@mans.edu.eg
- Phone: +201211182182
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.