Comparing PENG block and surgical infiltration for pain relief after hip replacement surgery

Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery

Not applicable Interventional CHU de Reims · NCT06257160

This study is testing whether a new pain relief method called the PENG block works better than a traditional injection for people recovering from hip replacement surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment194 (estimated)
Ages18 Years and up
SexAll
SponsorCHU de Reims Academic / other
Locations1 site (Reims)
Trial IDNCT06257160 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of two pain management techniques—ultrasound-guided PENG block and surgical infiltration—in patients undergoing posterior total hip replacement surgery. It is a randomized, double-blind, single-center trial conducted at Reims University Hospital, where patients will be assigned to receive either the PENG block or surgical infiltration for analgesia. The study seeks to determine if the PENG block provides superior pain relief without the side effects associated with traditional opioid use, thereby enhancing recovery and rehabilitation outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults scheduled for posterior total hip replacement surgery at Reims University Hospital who can provide informed consent.

Not a fit: Patients with severe comorbidities, allergies to local anesthetics, or those undergoing revision surgeries will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing hip replacement surgery, reducing reliance on opioids.

How similar studies have performed: While the PENG block is a newer technique with limited literature, initial results suggest promising efficacy, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* Patients eligible for posterior total hip replacement surgery at Reims University Hospital
* Patients agreeing to take part in the research and having signed the informed consent form
* Patients of full age
* Patients affiliated to a social security scheme

Exclusion criteria:

* Minor patients
* Patients protected by law
* Pregnant and breast-feeding women
* Patients with allergy to local anesthetics
* Patients with neuropathy
* Patients with an ASA score greater than or equal to 4
* Patients undergoing revision surgery on a total hip prosthesis
* Patients undergoing anterior total hip replacement surgery
* Patients suffering from a femur fracture
* Patients with a contraindication to Peng block.
* Patients refusing one of the proposed techniques.
* Persons deprived of their liberty by judicial or administrative decision.
* Persons under psychiatric care
* Persons unable to express their consent.

Where this trial is running

Reims

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hip ArthropathyHip ArthrosisAnalgesiaHipArthroplastyPENGlocoregional anesthesiainfiltration
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.