Comparing partial tooth restorations made with 3D printing versus CAD-CAM
Official title: Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM: A Split-Mouth Randomized Clinical Trial
Run by Cukurova University · NCT07031856 · Data updated 2026-11-12
This project will try two types of partial tooth restorations—one 3D-printed and one made with CAD-CAM—in people who need restorations on two teeth to see which one performs better using FDI clinical criteria.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 12 (estimated) |
| Sponsor | Cukurova University Academic / other |
| Locations | 1 site (Adana, Sarıçam) |
| Status | Recruiting |
| Started | July 1, 2025 |
| Main results expected | November 1, 2025 |
| Study ends | November 2026 |
| Registry record updated | April 2, 2026 |
| Trial ID | NCT07031856 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with two teeth needing partial restorations, stable periodontal health, good oral hygiene, no serious systemic diseases, and willingness to attend follow-up for two years are ideal candidates.
✕Probably not a fit
People with systemic illnesses that affect healing, severe bruxism, active gum disease or bone loss, pregnant or lactating women, or those allergic to materials used are unlikely to benefit or may be excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized split-mouth study will give each participant a CAD-CAM partial restoration on one tooth and a 3D-printed partial restoration on the other, then follow both restorations over time using FDI criteria. Participants are adults with two teeth requiring restorations, good periodontal stability, and the ability to attend follow-up visits over two years. Outcomes will compare clinical performance measures such as aesthetics, function, and biological response between the two fabrication methods. Patients with systemic conditions affecting healing, heavy bruxism, active periodontal disease, or pregnancy are excluded.
Why it matters
Potential benefit: If successful, the results could help patients get longer-lasting, better-fitting partial restorations and inform whether 3D printing offers advantages over CAD-CAM.
How similar studies have gone: CAD-CAM restorations have an established record of good clinical performance, while 3D-printed restorations are an emerging approach with promising short-term results but limited long-term comparative data.
Who can join: the full rules
Show full inclusion / exclusion criteria
İncluiding: \-- Patients with periodontally stable and appropriate oral hygiene habits without serious systemic diseases that preclude restoration. - Male and female patients with hard tissue loss in their mouth or with 2 teeth in need of restoration replacement (eligibility for split-mouth design). - People who can comply with the treatment and volunteer for follow-up for 2 years- Exclusion Criteria: Patients with systemic conditions that may affect the study process (e.g. diabetes, autoimmune diseases). * Patients with excessive bruxism or parafunctional habits. * Pregnant or lactating women. * Patients with gum disease or severe bone loss. * Patients with a history of allergic reactions.
Where it's running
-
Çukurova Üniversitesi Diş Hekimliği Fakültesi
Adana, Sarıçam, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Research Assistant
- Email: yarenncoskun@gmail.com
- Phone: +90 0544 745 8633
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.