Comparing pain relief techniques for patients undergoing video-assisted thoracic surgery

A Randomized Clinical Trial Comparing Transversus Thoracic Muscle Plane Block, Erector Spinae Plane Block and Paravertebral Block for Analgesia in Patients Undergoing Video-Assisted Thoracic Surgery

Not applicable Interventional Tanta University · NCT06987136

This study is testing three different pain relief methods to see which one works best for people recovering from video-assisted thoracic surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorTanta University Academic / other
Locations1 site (Tanta, El-Gharbia)
Trial IDNCT06987136 on ClinicalTrials.gov

What this trial studies

This study aims to compare three different regional anesthesia techniques—transversus thoracic muscle plane block (TTPB), erector spinae plane block (ESPB), and thoracic paravertebral block (TPVB)—to determine their effectiveness in providing postoperative analgesia for patients undergoing video-assisted thoracoscopic surgery (VATS). VATS is a minimally invasive surgical approach that offers advantages over traditional thoracotomy, including reduced pain and shorter recovery times. The study will evaluate the efficacy of these blocks in managing pain after surgery, potentially improving patient outcomes and comfort.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older scheduled for video-assisted thoracic surgery with ASA physical status I-II.

Not a fit: Patients with a body mass index over 30, coagulopathy, or a history of opiate abuse may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracic surgery.

How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status I-II.
* Scheduled for video-assisted thoracic surgery under general anesthesia.

Exclusion Criteria:

* Body mass index \>30 kg/m2.
* Coagulopathy.
* History of opiate abuse.
* Pre-existing chronic pain.
* Allergy to local anesthetics or analgesics.
* Infection at the site of injection.
* Mental or neurological disorders.
* Operation converted to open thoracotomy.
* Renal dysfunction (glomerular filtration rate (GFR) \< 50 ml/min).
* Pregnancy

Where this trial is running

Tanta, El-Gharbia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Transversus Thoracic Muscle Plane BlockErector Spinae Plane BlockParavertebral BlockAnalgesiaVideo-Assisted Thoracic Surgery
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.