Comparing pain relief methods for patients with rib fractures

Ultrasound-Guided Continuous Serratus Anterior Plane Block Versus Intravenous Dexmedetomidine Infusion for Pain Control in Patients With Multiple Rib Fractures: A Prospective Randomized Clinical Trial.

Phase 4 Interventional Beni-Suef University · NCT05965895

This study is testing whether a special pain relief technique using ultrasound can help people with multiple rib fractures feel better and recover faster compared to a medication infusion.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorBeni-Suef University Academic / other
Locations1 site (Banī Suwayf, Beni-Suef)
Trial IDNCT05965895 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of ultrasound-guided continuous serratus anterior plane block versus dexmedetomidine infusion for managing pain in patients with multiple rib fractures. It focuses on improving pain management to enhance pulmonary function and reduce complications associated with rib fractures. The study will involve patients with a rib fracture score greater than 7, assessing their pain relief and recovery outcomes. The goal is to determine which method provides better analgesia and supports recovery in thoracic trauma patients.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a rib fracture score greater than 7 and isolated multiple rib fractures.

Not a fit: Patients with multiple injuries, chronic pain conditions, or those who are intubated may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients with rib fractures, enhancing recovery and reducing complications.

How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥18 years
* Rib fracture score of more than 7
* Patient with isolated multiple rib fractures, ●American Society of Anesthesiologists classification of physical status \< IV
* Body mass index (BMI) ≤ 35.

Exclusion Criteria:

* Refusal of the patient
* Trauma survey include multiple injuries including head injuries, visceral and long bone fractures
* Intubated patients
* Known hypersensitivity to any study medication, ●Chronic opioid use or chronic pain patient, ●Hemodynamic instability
* Haemothorax or pneumothorax.

Where this trial is running

Banī Suwayf, Beni-Suef

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PainSerratus anteriorDexmedetomidineRibFractures
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.