Comparing pain relief methods during breast surgery
Official title: Efficacy of Single Level Versus Bilevel Serratus Anterior Plane Block With Dexmedetomidine During Breast Cancer Surgery
Run by National Cancer Institute, Egypt · NCT05361837 · Data updated 2026-11-12
This study is testing different ways to relieve pain during breast surgery for cancer patients to see which method works best.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | Women only |
| Enrollment | 172 (estimated) |
| Sponsor | National Cancer Institute, Egypt Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | May 10, 2022 |
| Main results expected | November 15, 2026 |
| Study ends | November 25, 2026 |
| Registry record updated | June 30, 2026 |
| Trial ID | NCT05361837 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are cancer patients aged 18-65 scheduled for modified radical mastectomy with an ASA classification of I-II.
✕Probably not a fit
Patients who may not benefit include those with coagulation defects, abnormal kidney or liver functions, local infections at the injection site, or those who refuse participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effectiveness of single-level and bilevel serratus anterior plane blocks, both with and without the addition of dexmedetomidine, in providing analgesia for cancer patients undergoing modified radical mastectomy. The aim is to assess pain control and potential side effects associated with these techniques. By evaluating different approaches to regional anesthesia, the study seeks to identify the most effective method for managing postoperative pain in this patient population.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast surgery.
How similar studies have gone: Other studies have shown promising results with serratus anterior plane blocks for pain management, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients scheduled for modified radical mastectomy, * Age 18-65 years, * ASA I-II Exclusion Criteria: * patient refusal, * coagulation defects, * abnormal kidney or liver functions, * local infection at site of injection.
Where it's running
-
Walaa Y Elsabeeny
Cairo, Cairo Governorate, Egypt Recruiting
Study contacts
- Principal investigator: Walaa Y Elsabeeny, MD — Assistant Professor of Anesthesia and Pain management
- Study coordinator: Walaa Y Elsabeeny, MD
- Email: walaa.elsabeeny@nci.cu.edu.eg
- Phone: 201007798466
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.