Clinical trial Recruiting at 1 site Interventional Ages 18 to 65 Women only

Comparing pain relief methods during breast surgery

Official title: Efficacy of Single Level Versus Bilevel Serratus Anterior Plane Block With Dexmedetomidine During Breast Cancer Surgery

Run by National Cancer Institute, Egypt · NCT05361837 · Data updated 2026-11-12

This study is testing different ways to relieve pain during breast surgery for cancer patients to see which method works best.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexWomen only
Enrollment172 (estimated)
SponsorNational Cancer Institute, Egypt
Academic / other
Locations1 site (Cairo, Cairo Governorate)
StatusRecruiting
StartedMay 10, 2022
Main results expectedNovember 15, 2026
Study endsNovember 25, 2026
Registry record updatedJune 30, 2026
Trial IDNCT05361837 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are cancer patients aged 18-65 scheduled for modified radical mastectomy with an ASA classification of I-II.

Probably not a fit

Patients who may not benefit include those with coagulation defects, abnormal kidney or liver functions, local infections at the injection site, or those who refuse participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of single-level and bilevel serratus anterior plane blocks, both with and without the addition of dexmedetomidine, in providing analgesia for cancer patients undergoing modified radical mastectomy. The aim is to assess pain control and potential side effects associated with these techniques. By evaluating different approaches to regional anesthesia, the study seeks to identify the most effective method for managing postoperative pain in this patient population.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast surgery.

How similar studies have gone: Other studies have shown promising results with serratus anterior plane blocks for pain management, suggesting that this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients scheduled for modified radical mastectomy,
* Age 18-65 years,
* ASA I-II

Exclusion Criteria:

* patient refusal,
* coagulation defects,
* abnormal kidney or liver functions,
* local infection at site of injection.

Where it's running

  • Walaa Y Elsabeeny
    Cairo, Cairo Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.