Comparing pain relief methods during breast surgery

Efficacy of Single Level Versus Bilevel Serratus Anterior Plane Block With Dexmedetomidine During Breast Cancer Surgery

NA · National Cancer Institute, Egypt · NCT05361837

This study is testing different ways to relieve pain during breast surgery for cancer patients to see which method works best.

Quick facts

PhaseNA
Study typeInterventional
Enrollment172 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorNational Cancer Institute, Egypt (other)
Locations1 site (Cairo)
Trial IDNCT05361837 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of single-level and bilevel serratus anterior plane blocks, both with and without the addition of dexmedetomidine, in providing analgesia for cancer patients undergoing modified radical mastectomy. The aim is to assess pain control and potential side effects associated with these techniques. By evaluating different approaches to regional anesthesia, the study seeks to identify the most effective method for managing postoperative pain in this patient population.

Who should consider this trial

Good fit: Ideal candidates for this study are cancer patients aged 18-65 scheduled for modified radical mastectomy with an ASA classification of I-II.

Not a fit: Patients who may not benefit include those with coagulation defects, abnormal kidney or liver functions, local infections at the injection site, or those who refuse participation.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast surgery.

How similar studies have performed: Other studies have shown promising results with serratus anterior plane blocks for pain management, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients scheduled for modified radical mastectomy,
* Age 18-65 years,
* ASA I-II

Exclusion Criteria:

* patient refusal,
* coagulation defects,
* abnormal kidney or liver functions,
* local infection at site of injection.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Analgesia

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.