Comparing pain relief methods after total knee replacement surgery
Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery. A Double Blind Randomized Clinical Trial.
This study is testing two different ways to block pain after knee replacement surgery to see which one helps patients feel better and recover faster.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 62 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Germans Trias i Pujol Hospital Academic / other |
| Locations | 1 site (Badalona, Barcelona) |
| Trial ID | NCT06514365 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of two different nerve block techniques for pain management in patients undergoing total knee replacement surgery. It compares the analgesic effects of a subsartorial saphenous block combined with either a popliteal sciatic block or an iPACK block. The goal is to determine which method provides better pain relief and motor function post-surgery. Participants will receive local anesthesia and will be monitored for pain levels and recovery outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with osteoarthritis scheduled for total primary knee arthroplasty.
Not a fit: Patients under 18, those requiring general anesthesia, or individuals with chronic pain management issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing total knee replacement, enhancing recovery and rehabilitation.
How similar studies have performed: While there are few studies on the iPACK block, this specific comparison of techniques has not been extensively tested, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with osteoarthritis scheduled for total primary knee arthroplasty with same surgeons * Locoregional anesthesia * Age equal to or greater than 18 years * Consent to participate in the study Exclusion Criteria: * Age under 18 years old * General anesthesia * Allergy to local anesthetics * Severe kidney failure (Cr ≥ 2mg / dL) * Chronic opioid use (over 3 months) * Chronic pregabalin / gabapentin use (more than 3 months) * Psychiatric illness that may interfere with the evaluation or follow-up
Where this trial is running
Badalona, Barcelona
- Hospital Universitari Germans Trias i Pujol — Badalona, Barcelona, Spain (Recruiting)
Study contacts
- Study coordinator: Madalina Dinu, Mrs
- Email: madidinu@hotmail.com
- Phone: 0034600349517
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.