Comparing pain relief methods after gallbladder surgery

Comparison of Postoperative Analgesic Efficacy of Quadratus Lumborum II, Quadratus Lumborum III and Paravertebral Blocks in Elective Laparoscopic Cholecystectomies

NA · Gaziosmanpasa Research and Education Hospital · NCT05943015

This study is testing which pain relief method works best after gallbladder surgery to help patients recover more comfortably.

Quick facts

PhaseNA
Study typeInterventional
Enrollment122 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorGaziosmanpasa Research and Education Hospital (other gov)
Locations1 site (Istanbul)
Trial IDNCT05943015 on ClinicalTrials.gov

What this trial studies

This trial aims to evaluate the effectiveness of different regional analgesia techniques, specifically Quadratus Lumborum II, Quadratus Lumborum III, and Paravertebral blocks, in providing postoperative pain relief for patients undergoing elective laparoscopic cholecystectomy. It is a prospective, randomized, single-center, single-blinded analysis that seeks to determine which method offers the best analgesic efficacy. The study addresses the need for effective pain management strategies to enhance recovery and reduce hospital stays following surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-65 with an American Society of Anesthesiologists physical status of I-II who are scheduled for elective laparoscopic cholecystectomy.

Not a fit: Patients with local anesthetic allergies, infections at the procedure site, a BMI over 35, anticoagulant use with bleeding disorders, chronic analgesia and opioid use, or mental and psychiatric disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing gallbladder surgery, potentially reducing opioid use and enhancing recovery.

How similar studies have performed: Other studies have shown promising results with regional analgesia techniques in similar surgical contexts, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-65 years, American Society of Anesthesiologists physical statusⅠ-II

Exclusion Criteria:

* local anesthetic allergy
* Infection at the procedure site
* Body Mass Index \>35 kg/m2
* Anticoagulant use with bleeding disorder
* Chronic analgesia and opioid use
* with mental and psychiatric disorders

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Postoperative Pain, paravertebral block, quadratus lumborum block, laparoscopic cholecystectomy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.