Comparing pain relief methods after breast cancer surgery
Effect of Erector Spinae Plane Block Versus Local Wound Infiltration on Postoperative Pain After Modified Radical Mastectomy
This study tests whether a new pain relief method using ultrasound-guided ESP block works better than regular local injections for people recovering from breast cancer surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 37 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | Female |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El Gharbyia) |
| Trial ID | NCT06533566 on ClinicalTrials.gov |
What this trial studies
This randomized prospective double-blinded study evaluates the effectiveness of ultrasound-guided Erector Spinae Plane (ESP) block versus local wound infiltration for managing postoperative pain in patients undergoing modified radical mastectomy. The study aims to determine which method provides better analgesia, reduces opioid consumption, and minimizes postoperative complications. By targeting the pain pathways through regional anesthesia, the ESP block may offer significant advantages over traditional local infiltration. The research is crucial as effective pain management can prevent the development of chronic pain in breast cancer surgery patients.
Who should consider this trial
Good fit: Ideal candidates are women scheduled for unilateral modified radical mastectomy with an ASA physical status of I-II.
Not a fit: Patients with neurological deficits, bleeding disorders, or those who are uncooperative may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast cancer surgery.
How similar studies have performed: Previous studies have shown that the Erector Spinae Plane block effectively alleviates postoperative pain and reduces opioid use, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiology (ASA) physical status I-II * scheduled for unilateral Modified radical mastectomy Exclusion Criteria: * Patient refusal. * Patient with neurological deficit. * Patient with bleeding disorders. * Uncooperative patient. * Infection at the block injection site. * Patients with history of allergy to local anesthetics. * Advanced hepatic, cardiac or renal failure. * Chronic opioid consumption. * Body mass index (BMI)≥ 30 kg m-2 * Chronic use of gabapentin or pregabalin
Where this trial is running
Tanta, El Gharbyia
- Faculty of medicine, Tanta university — Tanta, El Gharbyia, Egypt (Recruiting)
Study contacts
- Study coordinator: tarek A Mostafa, MD
- Email: dr.tarek311@yahoo.com
- Phone: 01003591332
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.