Comparing pain relief from gabapentin with and without physiotherapy for carpal tunnel syndrome
Official title: Pain Reduction of an Oral Gabapentin and Median Nerve Neural Mobilization Combined Treatment Compared to Only Oral Gabapentin in Subjects Who Suffer Carpal Tunnel Syndrome
Run by Universidad Europea de Madrid · NCT06778798 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study tests if adding physiotherapy to gabapentin can help people with carpal tunnel syndrome feel less pain and improve their hand function.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 21 (estimated) |
| Sponsor | Universidad Europea de Madrid Academic / other |
| Locations | 1 site (Valencia, Carabobo) |
| Trial ID | NCT06778798 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals diagnosed with unilateral carpal tunnel syndrome who can understand and communicate in Spanish.
✕Probably not a fit
Patients with cognitive impairments, recent surgeries, or those currently undergoing other pain treatments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of combining a physiotherapy technique called median nerve neural mobilization with oral gabapentin treatment for patients suffering from carpal tunnel syndrome. Participants will be randomly assigned to receive either the combination treatment or gabapentin alone, allowing for a direct comparison of pain reduction and upper limb functionality. The study aims to determine if the addition of physiotherapy enhances the overall treatment outcomes for this condition.
Why it matters
Potential benefit: If successful, this approach could provide a more effective pain management strategy for patients with carpal tunnel syndrome.
How similar studies have gone: Previous studies have shown promising results for combining physiotherapy with pharmacological treatments in pain management, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants must be medically diagnosed with unilateral carpal tunnel syndrome (with confirmative electrodiagnostic findings). * Full understanding of written and spoken Spanish (language). * Participants must freely consent to participate. * The presence of positive Phalen an Tinel sings. * The presence of carpal tunnel syndrome signs and symptoms Exclusion Criteria: * The lack to meet inclusion criterions, the presence of cognitive impairment, tumors, cancer, recent (affected) upper limb surgery or trauma, pregnancy, kinesiophobia, deformities of the (affected) upper limb, recent skin injuries or infections (in the affected upper limb), autoimmune inflammatory conditions or flu type symptoms, allergy to gabapentin, allergy to ibuprofen arginine, and also: participants must not be (during the present investigation) under any type of pain reducing treatment (conservative, homeopathic, invasive or not invasive)
Where it's running
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Ciudad Hospitalaria Enrique Tejera
Valencia, Carabobo, Venezuela Recruiting
Study contacts
- Principal investigator: Francisco Unda, PhD
- Study coordinator: Francisco Unda, PhD
- Email: 5299559@gmail.com
- Phone: 695634680
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Matrix Rhythm Therapy for Carpal Tunnel Syndrome
This study tests whether adding Matrix Rhythm Therapy to standard care helps people with mild-to-moderate carpal tunnel syndrome improve symptoms, hand function, grip and pinch strength, and quality of life.
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Carpal tunnel release vs placebo surgery in Finland
In this trial, people with carpal tunnel syndrome are randomly assigned to either standard carpal tunnel surgery or a pretend surgery to see if relief comes from the operation itself or from placebo effects.
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High-intensity laser therapy for carpal tunnel syndrome
This trial will test whether high-intensity laser therapy helps adults 18–65 with mild-to-moderate carpal tunnel syndrome reduce pain and improve nerve function and hand strength compared with a sham procedure.
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Ultrasound-guided needle release plus dextrose (D5W) hydrodissection for carpal tunnel syndrome
This trial tests whether combining ultrasound-guided partial release of the transverse carpal ligament with dextrose (D5W) hydrodissection provides better symptom relief for adults with carpal tunnel syndrome and at least moderate symptoms.
-
A mix of vitamins to help recovery after carpal tunnel surgery
This will test whether taking alpha-lipoic acid, vitamin E, and B vitamins helps adults recover better after carpal tunnel release surgery.
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Symptom spread and pain sensitivity in carpal tunnel syndrome
This test looks at whether people with carpal tunnel syndrome whose symptoms spread beyond the usual finger area have higher central pain sensitivity, using a questionnaire and pressure pain testing.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.