Comparing pain relief from exercise in arms and legs
Official title: Differences in Exercise-Induced Hypoalgesia at Local and Distal Levels Using Lower and Upper Limb Cycle Ergometer Protocols: A Randomized Controlled Trial in Healthy Participants
Run by Centro Universitario La Salle · NCT06283186 · Data updated 2026-11-12
This study tests if exercising your arms or legs can help reduce pain sensitivity in healthy people.
Quick facts
| Phase | Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 64 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Centro Universitario La Salle Academic / other |
| Locations | 1 site (Madrid) |
| Status | Recruiting |
| Started | April 23, 2024 |
| Main results expected | July 31, 2025 |
| Study ends | July 31, 2025 |
| Registry record updated | February 27, 2025 |
| Trial ID | NCT06283186 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy individuals aged 18 to 64 without any significant medical history.
✕Probably not a fit
Patients with cardiovascular, respiratory, metabolic, neurological, or osteomuscular conditions, as well as those experiencing pain, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial investigates how aerobic exercise affects pain sensitivity in healthy individuals by comparing three groups: one exercising on a lower limb cycle ergometer, another on an upper limb cycle ergometer, and a control group. Participants will engage in 30 minutes of aerobic activity at 70-80% of their heart rate reserve. The study will measure changes in pressure pain thresholds in both the thigh and elbow to assess exercise-induced hypoalgesia. The goal is to determine if the location of exercise influences pain relief in different body regions.
Why it matters
Potential benefit: If successful, this study could provide insights into effective pain management strategies through exercise.
How similar studies have gone: While the concept of exercise-induced hypoalgesia has been explored, this specific comparative approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Asymptomatic subjects aged between 18 and 64 years. Exclusion Criteria: * Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies. * History of epilepsy. * Pregnant * Pharmacological treatment. * Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 12 weeks.
Where it's running
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CSEU LaSalle
Madrid, Spain Recruiting
Study contacts
- Study coordinator: Álvaro Reina-Varona, MSc
- Email: alvaro.reina@lasallecampus.es
- Phone: 0034+649001863
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Comparing pain relief effects of upper and lower limb resistance training
This study tests whether doing resistance exercises for the upper or lower body can help healthy people feel less pain after working out.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.