Comparing pain control methods after lung surgery
Pain Control After VATS Anatomical Pulmonary Resections: Randomized Comparison Between Cryoanalgesia, Erector Spinae Plane Block and Epidural Catheter
NA · University Hospital Padova · NCT05993273
This study is testing which of three different pain control methods works best for people having lung surgery to help them feel better after the operation.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Padova (other) |
| Locations | 1 site (Padua) |
| Trial ID | NCT05993273 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of three different regional anesthesiological techniques—cryoanalgesia, epidural anesthesia, and erector spinae muscle plane block—in managing post-operative pain for patients undergoing video-assisted thoracoscopic surgery (VATS) for lung cancer. Patients will be randomized to receive one of the three techniques on the day of surgery, followed by a standard pain management protocol post-operatively. The goal is to determine which method provides the best pain relief and improves overall patient outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults undergoing anatomical pulmonary resections via VATS for either benign or malignant conditions.
Not a fit: Patients with chronic pain issues, those requiring intensive care post-surgery, or those with significant medical comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing lung surgery, enhancing their recovery experience.
How similar studies have performed: Previous studies have shown varying success with different regional anesthesia techniques, but this specific comparison is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all patients undergoing VATS anatomic pulmonary resection (lobectomy or segmentectomy) for benign or malignant disease Exclusion Criteria: * Refusal or inability to give informed consent to the study protocol * Age \< 18 years * Pregnancy * Allergies or contraindications to any of the treatments considered in the experimental design * Pre-operative use of pain medication for chronic pain or neuropathic pain * History of previous major chest surgery * American Society of Anesthesiologists (ASA) class \> 3 * Need for intensive care unit stay in the post-operative period * Patients undergoing anatomical pulmonary resections different than lobectomy or segmentectomy (bi-lobectomy or pneumonectomy). * Patients undergoing bronchial and/or vascular resections and reconstructions
Where this trial is running
Padua
- Thoracic Surgery Unit — Padua, Italy (RECRUITING)
Study contacts
- Principal investigator: MARCO MAMMANA, MD, PhD — PADUA UNIVERSITY HOSPITAL
- Study coordinator: MARCO MAMMANA, MD, PhD
- Email: marco.mammana@aopd.veneto.it
- Phone: +390498212442
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Lung Cancer, Pain, Postoperative, Thoracic Neoplasms, thoracoscopic surgery, post-operative pain, epidural anesthesia, ESP block, cryoanalgesia