Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Comparing pain and swelling after two types of endodontic microsurgery

Official title: Postoperative Symptoms Following Endodontic Microsurgery Performed by Piezoelectric Osteotomy Versus Conventional Osteotomy: A Randomized Clinical Trial

Run by King Abdullah University Hospital · NCT05898035 · Data updated 2026-11-12

This study is testing whether patients who have endodontic microsurgery feel less pain and swelling after using a traditional method compared to a newer technique.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment40 (estimated)
SponsorKing Abdullah University Hospital
Academic / other
Locations1 site (Irbid)
StatusRecruiting
StartedFebruary 1, 2022
Main results expectedDecember 12, 2024
Study endsSeptember 2025
Registry record updatedApril 8, 2025
Trial IDNCT05898035 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are non-smoking adults aged 18-65 with periodontally healthy teeth.

Probably not a fit

Patients with active systemic diseases, poor prognosis teeth, or those who are emotionally distressed may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate and compare postoperative pain, swelling, and quality of life in patients undergoing endodontic microsurgery using either conventional osteotomy or piezoelectric osteotomy. A total of 44 adult patients will be randomly assigned to one of the two techniques, and their postoperative experiences will be assessed through a standardized pain questionnaire at multiple time intervals. The study will be conducted at the postgraduate clinics of the Department of Conservative Dentistry at Jordan University of Science and Technology, with ethical approval obtained from the institutional review board. Participants will receive treatment free of charge, and their travel expenses for follow-up visits will be compensated.

Why it matters

Potential benefit: If successful, this study could lead to improved postoperative outcomes and quality of life for patients undergoing endodontic microsurgery.

How similar studies have gone: While the specific comparison of piezoelectric versus conventional osteotomy in endodontic microsurgery may be novel, similar studies in other surgical fields have shown promising results with piezoelectric techniques.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Non-smokers .
* Teeth that are periodontally healthy.
* Age (18-65)

Exclusion Criteria:

* Patients with an active systematic diseases that may affect the outcome
* Medically compromised patients on long term medications.
* Patients who had received analgesics or antibiotics prior to surgery will be postponed.
* Cases where orthograde endodontic treatment is feasible
* Teeth with poor prognosis.
* Teeth with an active periodontal disease (pocket depth \> 5 mm).
* Emotionally distressed patients.

Where it's running

  • Jordan University of Science and Technology
    Irbid, Jordan
    Recruiting

Study contacts

  • Principal investigator: Lama A Awawdeh, PhD — Jordan University of Science and Technolgoy
  • Study coordinator: Lama A Awawdeh, PhD
  • Email: lawawdeh@hotmail.com
  • Phone: +962795412954

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.