Comparing pain and swelling after two types of endodontic microsurgery

Postoperative Symptoms Following Endodontic Microsurgery Performed by Piezoelectric Osteotomy Versus Conventional Osteotomy: A Randomized Clinical Trial

Not applicable Interventional King Abdullah University Hospital · NCT05898035

This study is testing whether patients who have endodontic microsurgery feel less pain and swelling after using a traditional method compared to a newer technique.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorKing Abdullah University Hospital Academic / other
Locations1 site (Irbid)
Trial IDNCT05898035 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate and compare postoperative pain, swelling, and quality of life in patients undergoing endodontic microsurgery using either conventional osteotomy or piezoelectric osteotomy. A total of 44 adult patients will be randomly assigned to one of the two techniques, and their postoperative experiences will be assessed through a standardized pain questionnaire at multiple time intervals. The study will be conducted at the postgraduate clinics of the Department of Conservative Dentistry at Jordan University of Science and Technology, with ethical approval obtained from the institutional review board. Participants will receive treatment free of charge, and their travel expenses for follow-up visits will be compensated.

Who should consider this trial

Good fit: Ideal candidates for this study are non-smoking adults aged 18-65 with periodontally healthy teeth.

Not a fit: Patients with active systemic diseases, poor prognosis teeth, or those who are emotionally distressed may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved postoperative outcomes and quality of life for patients undergoing endodontic microsurgery.

How similar studies have performed: While the specific comparison of piezoelectric versus conventional osteotomy in endodontic microsurgery may be novel, similar studies in other surgical fields have shown promising results with piezoelectric techniques.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Non-smokers .
* Teeth that are periodontally healthy.
* Age (18-65)

Exclusion Criteria:

* Patients with an active systematic diseases that may affect the outcome
* Medically compromised patients on long term medications.
* Patients who had received analgesics or antibiotics prior to surgery will be postponed.
* Cases where orthograde endodontic treatment is feasible
* Teeth with poor prognosis.
* Teeth with an active periodontal disease (pocket depth \> 5 mm).
* Emotionally distressed patients.

Where this trial is running

Irbid

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pain PostoperativeSwelling Lips & FaceMicrosurgery, Pain, swelling, Piezo surgery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.