Comparing oxygen and CPAP for treating swimming induced pulmonary edema

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of continuous positive airway pressure (CPAP) compared to oxygen alone as a first-line treatment for swimming induced pulmonary edema (SIPE) in an out-of-hospital setting. It involves a large cohort of approximately 12,000 swimmers during Sweden's Vansbrosimningen event, where participants diagnosed with SIPE will receive either oxygen or oxygen with CPAP for 20 minutes. The primary outcome measure is the improvement in oxygen saturation assessed 10 minutes post-treatment. The goal is to provide effective treatment on-site, potentially reducing the need for emergency care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* clinical diagnosis of swimming induced pulmonary edema (SIPE) with need of acute treatment (oxygen saturation ≤91%)
* 18 years and older
* informed consent

Exclusion Criteria:

* declined consent
* suspected acute coronary syndrome
* severe asthma diagnosed together with pulmonary edema where beta-agonist-inhalation is needed prior to treatment of pulmonary edema
* hemodynamic instability or decreased consciousness

Where it's running

• Center of Clinical Research Dalarna
  Falun, Sweden Recruiting

Study contacts

• Study coordinator: Maria Hårdstedt, MD/PhD
• Email: maria.hardstedt@regiondalarna.se
• Phone: 46-738089464

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.