Comparing oral ibandronate with and without vitamin D for osteoporosis treatment

Examination of Bone Metabolism and Bone Mineral Density in Primary and Secondary Osteoporosis Treated by Oral Ibandronate

PHASE2 · Shinshu University · NCT03186131

This study tests if taking oral ibandronate for osteoporosis works better when combined with vitamin D compared to taking it alone.

Quick facts

PhasePHASE2
Study typeInterventional
Enrollment100 (estimated)
Ages20 Years and up
SexAll
SponsorShinshu University (other)
Locations1 site (Matsumoto, Nagano)
Trial IDNCT03186131 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the efficacy of oral ibandronate in treating osteoporosis, specifically comparing its effects when administered alone versus in combination with active vitamin D. The study aims to gather comparative data to determine if the addition of vitamin D enhances the treatment outcomes for patients with osteoporosis. Participants will be monitored for improvements in bone density and overall health. The trial is designed for patients who prefer oral medication for their osteoporosis management.

Who should consider this trial

Good fit: Ideal candidates for this study are osteoporotic patients who are interested in taking oral ibandronate.

Not a fit: Patients who are allergic to oral ibandronate or vitamin D, or those who have not taken oral ibandronate in the last two years may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective treatment option for patients with osteoporosis.

How similar studies have performed: There is limited comparative data available on this specific combination, making this approach relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Osteoporotic patients who want to take oral ibandronate

Exclusion Criteria:

* Patients who are allergic to oral ibandronate or vitamin D Patients who have not taken oral ibandronate for the last 2 years

Where this trial is running

Matsumoto, Nagano

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Osteoporosis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.