Comparing non-surgical and surgical treatments for furcation involvement in teeth

Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Patients With Furcation Involvement in Mandibular Molars - A Non-inferiority Randomized Controlled Trial

Not applicable Interventional Postgraduate Institute of Dental Sciences Rohtak · NCT06025955

This study is testing whether a non-surgical treatment or a surgical approach works better for people with gum disease affecting their back teeth.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment44 (estimated)
SexAll
SponsorPostgraduate Institute of Dental Sciences Rohtak Academic / other
Locations1 site (Rohtak, Haryana)
Trial IDNCT06025955 on ClinicalTrials.gov

What this trial studies

This study evaluates the outcomes of minimally invasive non-surgical therapy versus surgical therapy for patients with furcation involvement in mandibular molars. Patients diagnosed with generalized stage 3 periodontitis and grade 2 furcation involvement will be randomly assigned to either a non-surgical treatment group, which involves careful subgingival debridement, or a surgical group, which employs a minimally invasive flap technique. The study aims to assess clinical and patient-centered outcomes over a follow-up period of 3 to 6 months after treatment. The goal is to determine which approach yields better results in managing furcation defects.

Who should consider this trial

Good fit: Ideal candidates for this study are systemically healthy individuals with generalized stage 3 periodontitis and grade 2 furcation involvement in mandibular molars.

Not a fit: Patients who may not benefit from this study include those with recent periodontal surgery, smokers, or those with specific dental pathologies such as pulp or periapical issues.

Why it matters

Potential benefit: If successful, this study could provide patients with more effective treatment options for furcation involvement, potentially improving tooth retention and overall oral health.

How similar studies have performed: Other studies have shown promising results with minimally invasive techniques in periodontal treatment, suggesting that this approach may be beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Systemically healthy patients with diagnosis of generalized stage 3 periodontitis (Grade A or B) with at least one mandibular molar with FI (Degree 1 or 2-according to Hamp, 1975 and Subclass A or B- according to Tarnow and Fletcher, 1984), interproximal bone coronal to the furcation fornix and root trunk length ≤ cervical two thirds of the root length as measured on a periapical radiograph.
* Full mouth plaque score \< 30% after initial therapy
* Full mouth bleeding score \< 30% after initial therapy
* Having undergone a course of subgingival instrumentation in the past three months

Exclusion Criteria:

* Pregnant or lactating females
* Requiring antibiotic premedication
* Received antibiotic treatment in the previous 3 months
* Previous periodontal surgery in the last 1 year
* Smokers
* Pulpal or periapical pathology
* Third molar
* Non restorable tooth
* Trauma from occlusion

Where this trial is running

Rohtak, Haryana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Furcation DefectsOpen Flap DebridementPeriodontal Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.