Comparing muscle endurance in children with cystic fibrosis and healthy peers
Do Children With Cystic Fibrosis Differ in Muscle Endurance? A Comparative Study
This study is testing how muscle strength and endurance in children with cystic fibrosis compare to their healthy peers to better understand the physical challenges they face.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 6 Years to 18 Years |
| Sex | All |
| Sponsor | Bezmialem Vakif University Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06812793 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate and compare respiratory muscle strength, endurance, and core muscle endurance in children diagnosed with cystic fibrosis (CF) against healthy peers. By measuring various aspects of muscle endurance, including core and peripheral muscle endurance, the study seeks to understand the impact of CF on muscle function and overall physical capacity. The study includes children aged 6-18 years, with specific inclusion and exclusion criteria to ensure accurate assessments. The findings could provide insights into the physical challenges faced by children with CF and inform future interventions.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 6-18 diagnosed with cystic fibrosis and having a forced expiratory volume in one second (FEV1) above 40% of the predicted value.
Not a fit: Patients who may not benefit from this study include those with orthopedic, neurological, or vestibular issues that affect assessment methods, or those with a history of recent exacerbations or organ transplants.
Why it matters
Potential benefit: If successful, this study could enhance understanding of muscle endurance in children with cystic fibrosis, potentially leading to improved management strategies and interventions.
How similar studies have performed: While some studies have compared respiratory and lower extremity muscle endurance in children with CF, this specific focus on core muscle endurance is novel and has not been previously evaluated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria for Children with Cystic Fibrosis * Being between the ages of 6-18, * Being diagnosed with Cystic Fibrosis according to the American Cystic Fibrosis Association consensus guideline, * Having a forced expiratory volume in one second (FEV1) above 40% of the predicted value Exclusion Criteria for Children with Cystic Fibrosis * Not being able to cooperate with the assessment methods performed in the study * Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study * Having a history of exacerbation in the last month * Having an organ transplantation history * Using systemic corticosteroids Inclusion Criteria for Healthy Children - Being between the ages of 6-18 Exclusion Criteria for Healthy Children * Not being able to cooperate with the assessment methods performed in the study * Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study * Having had a respiratory tract infection in the last month
Where this trial is running
Istanbul
- Bezmialem Vakif University — Istanbul, Turkey (Recruiting)
Study contacts
- Study coordinator: Betul Cinar, PhD
- Email: betulbirik@gmail.com
- Phone: +905327879969
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.