Comparing Mulligan Mobilization and Proprioceptive Exercises for Knee Osteoarthritis

"Effectiveness of Mulligan Mobilization Technique and Proprioceptive Exercises Among Patients With Knee Osteoarthritis in Karachi" The Study Will Include Individuals Diagnosed With Knee OA, Aged 40 Years and Above, Clinically Diagnosed Mild to Moderate Primary OA in Knee. Participants Will be Recruited From a Physical Therapy Clinic, and Will be Screened for Inclusion and Exclusion Criteria. Inclusion Criteria Will Include Diagnosed Cases of Knee OA With Mild to Moderate Grade of OA (According to Kellgren and Lawrence Scale) and the Ability to Walk Without Assistive Device for at Least 50 Feet

NA · National Healthcare Center · NCT06971016

This study is testing whether a hands-on treatment called Mulligan mobilization works better than balance exercises for helping people aged 40 and older with mild to moderate knee osteoarthritis feel less pain and improve their movement.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages40 Years and up
SexAll
SponsorNational Healthcare Center (other)
Locations1 site (Karachi, Sindh)
Trial IDNCT06971016 on ClinicalTrials.gov

What this trial studies

This research analyzes the effectiveness of the Mulligan mobilization technique compared to proprioceptive exercises for treating patients with mild to moderate knee osteoarthritis. The study involves a 10-week assessment period where pain intensity, movement analysis, functional activities, balance performance, and quality of life improvements are evaluated. Participants aged 40 and above will undergo pre-test and post-test evaluations using various standardized assessment tools to measure the outcomes of the interventions. The study aims to provide robust data on physical therapy strategies for knee osteoarthritis.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 40 and above with mild to moderate knee osteoarthritis.

Not a fit: Patients with severe knee osteoarthritis or those who have undergone knee surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and functional outcomes for patients with knee osteoarthritis.

How similar studies have performed: Other studies have shown promising results with similar therapeutic approaches, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inclusion criteria will include diagnosed cases of knee OA with mild to moderate Grade of OA (According to Kellgren and Lawrence Scale)
* Ability to walk without assistive devices for at least 50 feet.

Exclusion Criteria:

* Patients have Kellgren and Lawrence \<grade 2 or above grade 3
* History of knee surgery, knee joint replacement
* Patients have been administered corticosteroid injections in last six months - - - History of mental illness, autoimmune disorder, neurological or orthopedic conditions affecting the lower limbs
* Presence of any other conditions that may affect balance or gait.

Where this trial is running

Karachi, Sindh

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Knee Osteoarthritis, Osteoarthritis, Mulligan Mobilization, Proprioceptive training, Pain, Functional Status, Knee Managment

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.