Comparing MRI and Ultrasound for Eye Layer Evaluation

MRI Versus Ocular UltraSonography for a Non Contact Evaluation of Ocular Layers

Observational Fondation Ophtalmologique Adolphe de Rothschild · NCT05300698

This study is testing whether MRI or ultrasound is better for looking at the layers of the eye in patients.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorFondation Ophtalmologique Adolphe de Rothschild Research network
Locations1 site (Paris, Paris)
Trial IDNCT05300698 on ClinicalTrials.gov

What this trial studies

This observational study aims to compare the effectiveness of MRI and ocular ultrasound in evaluating ocular layers. Participants will undergo both imaging techniques, with MRI involving the injection of a contrast agent for enhanced clarity. The study will monitor patients for any adverse effects post-MRI and collect data on their ophthalmological follow-up for one month. The goal is to identify discrepancies and agreements between the two imaging methods.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who require imaging for ocular diagnostics and can provide informed consent.

Not a fit: Patients with contraindications to MRI or gadolinium injection, as well as pregnant or breastfeeding women, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve diagnostic accuracy for ocular conditions by determining the most effective imaging technique.

How similar studies have performed: While there have been studies comparing imaging techniques, this specific approach of evaluating ocular layers using both MRI and ultrasound is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient over 18 years old
* Addressed in imaging for the realization of an ultrasound diagnostic eye
* Express consent to participate in the study
* Member of or beneficiary of a social security scheme

Exclusion Criteria:

* Patient with an absolute or relative contraindication to MRI (pacemaker or neurosensory stimulator or defibrillator implantable; ocular or cerebral ferromagnetic foreign body; claustrophobia)
* Absolute or relative contraindication to the injection of gadolinium (history of an allergic reaction to a product of contrast, bronchial asthma, allergic terrain, renal failure with serum creatinine clearance \<30 mL/min)
* Patient benefiting from a legal protection measure
* Pregnant or breastfeeding woman: a pregnancy test in the woman of childbearing age is to be carried out before inclusion

Where this trial is running

Paris, Paris

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Describe Ultrasound Matches and Disagreements Ocular and MRI
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.