Comparing MRI and Ultrasound for Eye Layer Evaluation
Official title: MRI Versus Ocular UltraSonography for a Non Contact Evaluation of Ocular Layers
Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT05300698 · Data updated 2026-11-12
This study is testing whether MRI or ultrasound is better for looking at the layers of the eye in patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris, Paris) |
| Status | Recruiting |
| Started | January 23, 2024 |
| Main results expected | February 2026 |
| Study ends | November 2026 |
| Registry record updated | January 5, 2026 |
| Trial ID | NCT05300698 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who require imaging for ocular diagnostics and can provide informed consent.
✕Probably not a fit
Patients with contraindications to MRI or gadolinium injection, as well as pregnant or breastfeeding women, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to compare the effectiveness of MRI and ocular ultrasound in evaluating ocular layers. Participants will undergo both imaging techniques, with MRI involving the injection of a contrast agent for enhanced clarity. The study will monitor patients for any adverse effects post-MRI and collect data on their ophthalmological follow-up for one month. The goal is to identify discrepancies and agreements between the two imaging methods.
Why it matters
Potential benefit: If successful, this study could improve diagnostic accuracy for ocular conditions by determining the most effective imaging technique.
How similar studies have gone: While there have been studies comparing imaging techniques, this specific approach of evaluating ocular layers using both MRI and ultrasound is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient over 18 years old * Addressed in imaging for the realization of an ultrasound diagnostic eye * Express consent to participate in the study * Member of or beneficiary of a social security scheme Exclusion Criteria: * Patient with an absolute or relative contraindication to MRI (pacemaker or neurosensory stimulator or defibrillator implantable; ocular or cerebral ferromagnetic foreign body; claustrophobia) * Absolute or relative contraindication to the injection of gadolinium (history of an allergic reaction to a product of contrast, bronchial asthma, allergic terrain, renal failure with serum creatinine clearance \<30 mL/min) * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman: a pregnancy test in the woman of childbearing age is to be carried out before inclusion
Where it's running
-
Hopital Fondation Adolphe de Rothschild
Paris, Paris, France Recruiting
Study contacts
- Study coordinator: Amélie Yavchitz, PhD
- Email: ayavchitz@for.paris
- Phone: 0148036454
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.