Comparing methods to measure bone density using CT scans

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates different calibration methods for quantifying bone mineral density (BMD) using CT scans, aiming to improve the diagnosis and management of osteoporosis. It focuses on patients who are undergoing CT scans of the lumbosacral spine or abdomen, assessing the effectiveness of phantomless calibration techniques. By analyzing the data collected from these scans, the study seeks to enhance the detection of fracture risk associated with osteoporosis. The goal is to provide a more accessible and accurate means of diagnosing this prevalent condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Both sexes.
* All ethnicities.
* Age equal or above 18 years.
* Any clinical indication (no specific pathology is required) for a CT scan of the lumbosacral spine or abdomen in which the entire lumbar spine (L1 to L5), paravertebral muscles, abdominal aorta, and subcutaneous adipose tissue are visible.
* Ability to give informed consent.

Exclusion Criteria:

* General contraindications to CT examination, including pregnancy or body weight/size exceeding scanner limits.
* Severe degenerative manifestations of the lumbosacral spine.
* Severe scoliosis of the lumbosacral spine.
* Surgical hardware that prevents adequate CT scanning.
* Oncologic pathology in progress or in recent history.
* Any other situation deemed incompatible with the study by the designated physician or investigator.

Where it's running

• The Rizzoli Orthopaedic Institute
  Bologna, Bo, Italy Recruiting
• Auckland Hospital - Greenlane Clinical Centre - National Women's Hospital
  Auckland, New Zealand Not yet recruiting

Study contacts

• Study coordinator: Alberto Bazzocchi, MD
• Email: alberto.bazzocchi@ior.it
• Phone: 051636

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Role of LH and hCG in adults being evaluated for endocrine disorders

  This study looks at whether levels of luteinizing hormone (LH) and hCG in adults undergoing endocrine evaluation relate to their disease presence and outcomes.

  Recruiting Copenhagen University Hospital at Herlev · Herlev · NCT07824102

• Can a blood marker called lumican reveal hidden fragility in postmenopausal osteoporosis

  This study tests whether serum lumican levels can help identify hidden fragility risk in postmenopausal women beyond what bone density shows.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07677072

• Functional Muscle-Bone Incongruity Index: A look at muscle strength and bone health in adults

  This observational study tests a composite FKUI score using handgrip strength and hip/spine bone density to see if it better reflects musculoskeletal health than each measure alone in adults undergoing routine DXA.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07677033

• Vessel-X Bone Filling Container System for Vertebral Augmentation

  A new minimally invasive vertebral augmentation approach tests the Vessel-X device to see if it safely improves pain and function in people with osteoporotic vertebral compression fractures.

  Recruiting at 2 sites National Defense Medical Center, Taiwan · Taipei and 1 other locations · NCT07665424

• Proximal Humerus Cortical Thickness in Post-Stroke Paresis

  This study tests whether measurements of the outer bone thickness of the upper arm (the humerus) on the paretic side after a stroke reflect regional bone loss and how well they agree with standard bone density tests.

  Recruiting Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Istanbul · NCT07651306

• People with Osteoporosis: See if Walk-BEST Gait Program Helps You Walk Safer

  This pilot study tests whether older adults with osteoporosis can use the Walk-BEST gait training with a wearable sensor to walk more safely and reduce fall risk.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07621679

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.