Comparing methods for closing the radial forearm donor site after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates two techniques for closing the donor site after using the radial forearm free flap (RFFF) in head and neck reconstruction. The study compares the split-thickness skin graft (STSG) method, which involves taking skin from the thigh, to the hatchet flap method, which uses local tissue from the forearm. Researchers will assess aesthetic and functional outcomes reported by patients to determine which closure technique yields better results. The focus is on improving postoperative quality of life by minimizing donor site complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 or older
* Oral cavity disease (malignant or benign) requiring radial forearm free flap reconstruction

Exclusion Criteria:

* Serious medical comorbidities including metastatic disease or other contraindications to surgery
* Any pre-existing condition affecting the use of both hands, including previous major scars
* Unable or unwilling to complete post-operative questionnaires in English
* Pregnant or lactating women

Where it's running

• Vancouver General Hospital
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Study coordinator: Eitan Prisman, MD, FRCSC
• Email: eitan.prisman@ubc.ca
• Phone: 6048754126

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Improving jaw reconstruction for oral cancer patients using virtual planning

  This study is testing if using virtual planning for jaw surgery can help oral cancer patients heal better and have a better quality of life compared to traditional surgery methods.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT05429099

• Donor ankle sensorimotor recovery after ACL reconstruction with a peroneus longus graft

  This study tests how the donor ankle recovers sensorimotor function after ACL reconstruction using a peroneus longus tendon autograft in adults 18–55.

  Recruiting Gazi University · Çankaya, Ankara · NCT07762989

• Intratumoral fluorescent nivolumab before surgery in head and neck cancer

  This study tests injecting fluorescently labeled nivolumab directly into head and neck tumors to see if it is safe and whether it reaches nearby lymph nodes before surgical removal.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07741565

• AI-assisted prehabilitation to help oral cancer patients return to work

  This trial will test an AI-assisted prehabilitation program to help adults with oral cancer reduce physical and emotional problems and return to work.

  Recruiting at 4 sites Taipei Veterans General Hospital, Taiwan · Taipei and 4 other locations · NCT07562100

• AI tool to measure jaw, neck, and shoulder movement for oral cancer care

  This project tests an AI system that automatically measures jaw, neck, and shoulder movement for people with or recovering from oral cancer and compares its readings to manual measurements.

  Recruiting National Taiwan University Hospital · Taipei · NCT07509619

• Blue light to speed healing of donor-site wounds after skin grafts

  This study will try adding blue light therapy to usual care to see if donor-site wounds heal faster and with less pain or infection in adults with intermediate-to-deep burns who need skin grafts.

  Recruiting AUSL Romagna Rimini · Cesena, Forlì-Cesena · NCT07453927

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.