Comparing magnetic stimulation methods for treating ventricular tachycardia storms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of two different strategies of transcranial magnetic stimulation (TcMS) in patients experiencing ventricular tachycardia (VT) storms. It is a three-arm randomized trial that compares TcMS with theta burst stimulation (TBS) and low-frequency TcMS against a sham stimulation group. The primary hypothesis is that TcMS will significantly reduce the burden of VT within 24 hours post-randomization compared to sham stimulation. The study aims to determine which TcMS approach is more effective in managing this critical condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ≥3 episodes of sustained VT or appropriate ICD therapies within 24 hours despite the use of at least one antiarrhythmic drug

Exclusion Criteria:

* Plan for catheter ablation of VT in the next 24 hours
* Pregnancy
* Contraindication to TcMS (i.e. implantable ventricular assist device, metal implanted in the head or neck \[except the mouth\], implanted medication pumps, cochlear implant, implanted brain stimulator, ocular implant, history of malignancy in the neck)

Where it's running

• Hospital of the University of Pennsylvania
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Study coordinator: Timothy Markman
• Email: timothy.markman@pennmedicine.upenn.edu
• Phone: 215-615-4332

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.