Comparing lung imaging techniques in infants

Comparison of Computertomography Scan, Electrical Impedance Tomography, and Ultrasound of the Lung in Infants - a Prospective Explorative Observational Study

Observational Medical University of Vienna · NCT04989439

This study is testing different lung imaging methods in infants to see which one best helps doctors understand lung problems like collapse or over-inflation.

Quick facts

Study typeObservational
Enrollment10 (estimated)
AgesN/A to 12 Months
SexAll
SponsorMedical University of Vienna Academic / other
Drugs / interventionsradiation
Locations1 site (Vienna)
Trial IDNCT04989439 on ClinicalTrials.gov

What this trial studies

This study examines the effectiveness of different lung imaging methods, specifically computed tomography (CT), electrical impedance tomography (EIT), and ultrasound, in infants. It aims to differentiate between collapsed and hyperinflated lung areas and to identify common elements among these imaging modalities. The research will involve infants hospitalized at the Medical University of Vienna who are scheduled for a CT scan, allowing for a direct comparison of these techniques. The study seeks to generate hypotheses for the bedside application of EIT and lung ultrasound in clinical settings.

Who should consider this trial

Good fit: Ideal candidates for this study are infants up to 12 months old who are hospitalized and scheduled for a CT scan of the thorax.

Not a fit: Patients with unstable cardiovascular, respiratory, or neurological conditions, or those with recent sternotomy or thoracic skin lesions, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve lung imaging techniques in infants, leading to better diagnosis and management of respiratory conditions.

How similar studies have performed: While EIT has shown promise in adult patients, this study represents a novel approach as there are no prior investigations comparing EIT with CT scans specifically in newborns and infants.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients hospitalized at the Department of Pediatrics of the Medical University of Vienna who will get a CT scan of the thorax.
* Patients aged up to 12 months

Exclusion Criteria:

* Unstable cardiovascular, respiratory and/or neurological conditions.
* Sternotomy during the previous 15 days.
* Thoracic skin lesions or wounds (including burns) on the thorax, where the EIT-electrode-belt would be placed.

Where this trial is running

Vienna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Infant ALLComputed TomographyElectric ImpedanceUltrasonographyLung InjuryCT, electrical impedance tomography, ultrasound
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.