Comparing local and systemic dexmedetomidine for pain relief in kidney surgeries
Systemic Versus Local Dexamedetomedine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block in Kidney Exploration Surgeries ,A Randomized Controlled Trial
This study is testing whether using dexmedetomidine locally or throughout the body can help manage pain better during kidney surgeries, aiming to improve recovery for patients.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Aswan University Academic / other |
| Locations | 1 site (Aswān, Aswan Governorate) |
| Trial ID | NCT06386770 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of local versus systemic dexmedetomidine as an adjuvant to bupivacaine in providing analgesia during erector spinae blocks for kidney exploration surgeries. The goal is to determine which method offers better pain management, potentially leading to improved recovery outcomes for patients. The erector spinae plane block is a newer technique that utilizes ultrasound guidance to enhance precision and minimize complications. By optimizing pain control, the study aims to facilitate early mobilization and reduce the risk of chronic pain following surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are ASA I/II patients undergoing kidney exploration surgeries with a BMI of less than 35.
Not a fit: Patients with a history of opioid use prior to surgery, local infections at the injection site, or those classified as ASA III/IV may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve postoperative pain management and enhance recovery for patients undergoing kidney surgeries.
How similar studies have performed: Other studies have shown promising results with similar approaches using dexmedetomidine as an adjuvant in regional anesthesia, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: •. kidney exploration surgeries. * ASA I/II patients. * BMI \<35 Exclusion Criteria: * Getting opioid analgesics prior to surgery. * Local infections at the site where needle for block is to be inserted. * ASAIII/IV. * Pregnancy. * History of drug addiction or alcohol abuse or a psychiatric illness,
Where this trial is running
Aswān, Aswan Governorate
- Aswan University — Aswān, Aswan Governorate, Egypt (Recruiting)
Study contacts
- Principal investigator: Ayman M Eldemrdash — Aswan University
- Study coordinator: Tarek s Hemaida, MD
- Email: dr.tarek@aswu.edu.eg
- Phone: 0100 736 3190
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.