Comparing linear and circular staplers for esophagojejunostomy after total gastrectomy
Linear Stapler Versus Circular Stapler in Esophagojejunostomy for Patients With Gastric Cancer Underwent Laparoscopic Total Gastrectomy
This study is testing whether using linear staplers or circular staplers during surgery can help patients with gastric cancer have fewer complications and shorter hospital stays after having their stomach removed.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Nanchong Central Hospital Government |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Nanchong, Sichuan) |
| Trial ID | NCT05360069 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of linear staplers versus circular staplers in performing esophagojejunostomy for patients with gastric cancer who have undergone total gastrectomy. It aims to determine which stapler type leads to fewer postoperative complications, reduced operative time, and lower hospital costs. The study will involve patients with histologically confirmed adenocarcinoma of the stomach, specifically those classified as Siewert type II and III. By comparing outcomes between the two stapler methods, the research seeks to provide evidence for optimal surgical practices in this patient population.
Who should consider this trial
Good fit: Ideal candidates are patients with histologically confirmed adenocarcinoma of the stomach at stages T1-T4 and an Eastern Cooperative Oncology Group performance status of 0 or 1.
Not a fit: Patients with distant metastasis, significant esophageal invasion, or those who have received prior chemotherapy or radiation therapy for other malignancies may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced healthcare costs for patients undergoing total gastrectomy.
How similar studies have performed: While there is limited evidence directly comparing these two stapler types, similar studies in surgical techniques have shown varying degrees of success, indicating the potential for valuable insights from this research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages. 2. Eastern Cooperative Oncology Group performance status of 0 or 1. 3. Adequate organ function. Exclusion Criteria: 1. Patients had distant metastasis. 2. oesophageal invasion of more than 3 cm. 3. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma. 4. Previous chemotherapy or radiation therapy for any other malignancies.
Where this trial is running
Nanchong, Sichuan
- Yunhong Tian — Nanchong, Sichuan, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.