Clinical trial Recruiting at 1 site Interventional Ages 18 to 90

Comparing linear and circular staplers for esophagojejunostomy after total gastrectomy

Official title: Linear Stapler Versus Circular Stapler in Esophagojejunostomy for Patients With Gastric Cancer Underwent Laparoscopic Total Gastrectomy

Run by Nanchong Central Hospital · NCT05360069 · Data updated 2026-11-12

This study is testing whether using linear staplers or circular staplers during surgery can help patients with gastric cancer have fewer complications and shorter hospital stays after having their stomach removed.

Quick facts

Study typeInterventional
Ages18 Years to 90 Years
SexAll
Enrollment100 (estimated)
SponsorNanchong Central Hospital
Government
Drugs / interventionschemotherapy, radiation
Locations1 site (Nanchong, Sichuan)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedApril 2, 2026
Trial IDNCT05360069 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with histologically confirmed adenocarcinoma of the stomach at stages T1-T4 and an Eastern Cooperative Oncology Group performance status of 0 or 1.

Probably not a fit

Patients with distant metastasis, significant esophageal invasion, or those who have received prior chemotherapy or radiation therapy for other malignancies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of linear staplers versus circular staplers in performing esophagojejunostomy for patients with gastric cancer who have undergone total gastrectomy. It aims to determine which stapler type leads to fewer postoperative complications, reduced operative time, and lower hospital costs. The study will involve patients with histologically confirmed adenocarcinoma of the stomach, specifically those classified as Siewert type II and III. By comparing outcomes between the two stapler methods, the research seeks to provide evidence for optimal surgical practices in this patient population.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced healthcare costs for patients undergoing total gastrectomy.

How similar studies have gone: While there is limited evidence directly comparing these two stapler types, similar studies in surgical techniques have shown varying degrees of success, indicating the potential for valuable insights from this research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages.
2. Eastern Cooperative Oncology Group performance status of 0 or 1.
3. Adequate organ function.

Exclusion Criteria:

1. Patients had distant metastasis.
2. oesophageal invasion of more than 3 cm.
3. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma.
4. Previous chemotherapy or radiation therapy for any other malignancies.

Where it's running

  • Yunhong Tian
    Nanchong, Sichuan, China
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.