Comparing linear and circular staplers for esophagojejunostomy after total gastrectomy
Official title: Linear Stapler Versus Circular Stapler in Esophagojejunostomy for Patients With Gastric Cancer Underwent Laparoscopic Total Gastrectomy
Run by Nanchong Central Hospital · NCT05360069 · Data updated 2026-11-12
This study is testing whether using linear staplers or circular staplers during surgery can help patients with gastric cancer have fewer complications and shorter hospital stays after having their stomach removed.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Nanchong Central Hospital Government |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Nanchong, Sichuan) |
| Status | Recruiting |
| Started | January 1, 2020 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2028 |
| Registry record updated | April 2, 2026 |
| Trial ID | NCT05360069 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with histologically confirmed adenocarcinoma of the stomach at stages T1-T4 and an Eastern Cooperative Oncology Group performance status of 0 or 1.
✕Probably not a fit
Patients with distant metastasis, significant esophageal invasion, or those who have received prior chemotherapy or radiation therapy for other malignancies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of linear staplers versus circular staplers in performing esophagojejunostomy for patients with gastric cancer who have undergone total gastrectomy. It aims to determine which stapler type leads to fewer postoperative complications, reduced operative time, and lower hospital costs. The study will involve patients with histologically confirmed adenocarcinoma of the stomach, specifically those classified as Siewert type II and III. By comparing outcomes between the two stapler methods, the research seeks to provide evidence for optimal surgical practices in this patient population.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced healthcare costs for patients undergoing total gastrectomy.
How similar studies have gone: While there is limited evidence directly comparing these two stapler types, similar studies in surgical techniques have shown varying degrees of success, indicating the potential for valuable insights from this research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages. 2. Eastern Cooperative Oncology Group performance status of 0 or 1. 3. Adequate organ function. Exclusion Criteria: 1. Patients had distant metastasis. 2. oesophageal invasion of more than 3 cm. 3. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma. 4. Previous chemotherapy or radiation therapy for any other malignancies.
Where it's running
-
Yunhong Tian
Nanchong, Sichuan, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.