Comparing light and moderate exercise for people with Myasthenia Gravis
Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis
This study is testing whether light exercise is just as helpful as moderate exercise for people with Myasthenia Gravis over 12 weeks of group sessions.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | HealthPartners Institute Academic / other |
| Locations | 1 site (Saint Paul, Minnesota) |
| Trial ID | NCT06491238 on ClinicalTrials.gov |
What this trial studies
This pilot study aims to evaluate the feasibility, acceptability, and tolerability of light versus moderate intensity exercise in adults diagnosed with Myasthenia Gravis. Participants will be enrolled in the NeuroWell exercise program at the HealthPartners Neuroscience Center, where they will engage in small group exercise sessions three times a week for 12 weeks. They will be randomly assigned to either a light intensity or moderate intensity exercise group. The study hypothesizes that both exercise intensities will be manageable and that the light intensity group can achieve similar health improvements as the moderate intensity group.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18-80 with a diagnosis of generalized Myasthenia Gravis who are on a stable medication regimen.
Not a fit: Patients who are non-English speaking, have significant cognitive impairments, or have serious comorbid conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into safe exercise regimens for patients with Myasthenia Gravis, potentially improving their health outcomes.
How similar studies have performed: While this approach is relatively novel, previous studies have indicated that exercise can be beneficial for individuals with neurological disorders, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ability to provide and provision of signed and dated informed consent form. * Age 18-80 * Diagnosis of generalized MG. * On a stable MG prescription medication regimen for the last 3 months. Exclusion Criteria: * Non-English speaking * Regular exercise participation within the month prior to study enrollment or any outside exercise participation during the study intervention period. * Significant cognitive impairment of any etiology that would impact study participation. * History of heart failure, chronic lung disease, angina or any other condition that causes unreasonable shortness of breath on exertion. * History of any serious neurological, psychiatric, or substance use disorders that would impact study participation. * Women who are currently pregnant or planning to become pregnant during the study. * Any other medical conditions that could affect their ability to participate in exercise for the study duration (as determined by study investigators). * Active participation or past participation ≤3 months in any other interventional research study. * Unwilling to participate in all study related activities.
Where this trial is running
Saint Paul, Minnesota
- HealthPartners Neuroscience Center — Saint Paul, Minnesota, United States (Recruiting)
Study contacts
- Study coordinator: Clinical Trials Coordinator
- Email: ClinicalTrials@HealthPartners.com
- Phone: 651-495-6363
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.