Comparing light and moderate exercise for people with Myasthenia Gravis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study aims to evaluate the feasibility, acceptability, and tolerability of light versus moderate intensity exercise in adults diagnosed with Myasthenia Gravis. Participants will be enrolled in the NeuroWell exercise program at the HealthPartners Neuroscience Center, where they will engage in small group exercise sessions three times a week for 12 weeks. They will be randomly assigned to either a light intensity or moderate intensity exercise group. The study hypothesizes that both exercise intensities will be manageable and that the light intensity group can achieve similar health improvements as the moderate intensity group.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ability to provide and provision of signed and dated informed consent form.
* Age 18-80
* Diagnosis of generalized MG.
* On a stable MG prescription medication regimen for the last 3 months.

Exclusion Criteria:

* Non-English speaking
* Regular exercise participation within the month prior to study enrollment or any outside exercise participation during the study intervention period.
* Significant cognitive impairment of any etiology that would impact study participation.
* History of heart failure, chronic lung disease, angina or any other condition that causes unreasonable shortness of breath on exertion.
* History of any serious neurological, psychiatric, or substance use disorders that would impact study participation.
* Women who are currently pregnant or planning to become pregnant during the study.
* Any other medical conditions that could affect their ability to participate in exercise for the study duration (as determined by study investigators).
* Active participation or past participation ≤3 months in any other interventional research study.
* Unwilling to participate in all study related activities.

Where it's running

• HealthPartners Neuroscience Center
  Saint Paul, Minnesota, United States Recruiting

Study contacts

• Study coordinator: Clinical Trials Coordinator
• Email: ClinicalTrials@HealthPartners.com
• Phone: 651-495-6363

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• ADAPT Forward master protocol testing multiple regimens for generalized myasthenia gravis

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.