Comparing laser puncture and ultraviolet radiation for treating polycystic ovarian syndrome in obese women
Effect of Laser Puncture Versus Ultraviolet Radiation on Women With Polycystic Ovarian Syndrome
This study is testing whether laser puncture or ultraviolet radiation can help obese women aged 25 to 35 with polycystic ovarian syndrome feel better compared to those just taking metformin.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 20 Years to 35 Years |
| Sex | Female |
| Sponsor | Cairo University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05986838 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of laser puncture and ultraviolet radiation on obese women aged 25 to 35 with polycystic ovarian syndrome (PCOS). Participants will be divided into three groups: one receiving laser puncture, another receiving ultraviolet radiation, and a control group receiving only metformin. Each intervention will occur three times a week for three months, with assessments of follicular size via ultrasound and hormonal levels through blood tests. The goal is to evaluate the effectiveness of these treatments in managing PCOS symptoms.
Who should consider this trial
Good fit: Ideal candidates are obese women aged 25 to 35 with a BMI between 30 and 40 who have been diagnosed with polycystic ovarian syndrome.
Not a fit: Patients with a BMI over 40, those with hyperprolactinemia, or other significant endocrinological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide new treatment options for managing symptoms of polycystic ovarian syndrome in obese women.
How similar studies have performed: While there is limited data on the specific combination of laser puncture and ultraviolet radiation for PCOS, similar interventions have shown promise in managing related symptoms.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Obese nulli gravid PCOS women * BMI 30-40 kg/m2 Exclusion Criteria: * hyperprolactinemia * BMI \> 40 kg/m2 Endocrinological disorders such as thyroid disease, Cushing's syndrome, Coagulopathy * Recent use of oral contraceptive pills * Recent use of any photosensitizing medications, such as aspirin, tetracycline, chlorothiazide, or psoralen suspicious of neoplasms
Where this trial is running
Cairo
- Kasr Alainy medical school — Cairo, Egypt (Recruiting)
Study contacts
- Principal investigator: Ahmed M Maged — Cairo University
- Study coordinator: Ahmed M Maged
- Email: Ahmedmaged@cu.edu.eg
- Phone: +201005227404
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.