Comparing inspiratory muscle training and aerobic exercise for post-COVID-19 recovery
Comparison the Effects of Inspiratory Muscle Training and High Intensity Interval Aerobic Exercise Training in Patients With Post COVID-19
This study is testing whether breathing exercises or high-intensity workouts can help people recovering from COVID-19 feel better and improve their ability to exercise.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Gazi University Academic / other |
| Locations | 1 site (Ankara) |
| Trial ID | NCT05381779 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effects of inspiratory muscle training and high-intensity interval aerobic exercise training on patients recovering from COVID-19. It addresses common post-COVID symptoms such as dyspnea, fatigue, and decreased exercise capacity. The primary outcome will be measured through oxygen consumption during a cardiopulmonary exercise test, while secondary outcomes will include muscle oxygenation and physical activity levels. Participants will be divided into three groups: inspiratory muscle training, high-intensity interval training, and a control group.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-75 who have been diagnosed with COVID-19 and are willing to participate.
Not a fit: Patients with significant comorbidities or contraindications to exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve recovery outcomes and quality of life for patients suffering from long-term effects of COVID-19.
How similar studies have performed: Previous studies have shown positive effects of inspiratory muscle training and aerobic exercise in patients with lung diseases, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between the ages of 18-75 * Diagnosed with COVID-19 * COVID-19 Polymerase Chain Reaction (PCR) test result negative * Volunteer to participate in the study Exclusion Criteria: * Body mass index \>35 kg/m2 * Acute pulmonary exacerbation, acute upper or lower respiratory tract infection * Aortic stenosis, complex arrhythmia, aortic aneurysm * Serious neurological, neuromuscular, orthopedic, other systemic diseases or other diseases affecting physical functions * Cognitive impairment that causes difficulty in understanding and following exercise test instructions * Participated in a planned exercise program in the last three months * Bulla formation in the lung * Uncontrolled hypertension and/or diabetes mellitus, heart failure and cardiovascular disease * Contraindication for exercise testing and/or exercise training according to the American College of Sports Medicine
Where this trial is running
Ankara
- Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Clinic — Ankara, Turkey (Recruiting)
Study contacts
- Principal investigator: Başak KAVALCI KOL, Pt. MSc. — Gazi University
- Study coordinator: Meral BOŞNAK GÜÇLÜ, Prof.Dr.
- Email: meralbosnak@gazi.edu.tr
- Phone: +903122162647
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.