Comparing imaging techniques for diagnosing tumors in children and young adults
Official title: Pediatric PET/MR Image Registry
Run by Stanford University · NCT03458520 · Data updated 2026-11-12
This study is testing which imaging method works best for diagnosing tumors in children and young adults by comparing MR imaging, PET/MR imaging, and PET/CT imaging.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 40 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Stanford University Academic / other |
| Locations | 1 site (Palo Alto, California) |
| Status | Recruiting |
| Started | February 1, 2018 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 9, 2026 |
| Trial ID | NCT03458520 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include children and young adults with proven solid tumors or newly diagnosed masses suspected to be solid tumors.
✕Probably not a fit
Patients with contraindications for MRI or PET/MR, such as those with cardiac pacemakers or CNS primary tumors, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate and compare the effectiveness of whole body magnetic resonance (MR) imaging, whole body positron emission tomography (PET)/MR imaging, and PET/Computed Tomography (CT) imaging in diagnosing tumors in pediatric and young adult patients. The study will assess the sensitivities, specificities, and diagnostic accuracies of these imaging modalities to identify significant differences in their performance. Participants will include those with confirmed solid tumors or suspected solid tumors, and the study will collect data for analysis in an image registry.
Why it matters
Potential benefit: If successful, this study could enhance diagnostic accuracy for tumors in children and young adults, leading to better treatment outcomes.
How similar studies have gone: Other studies have shown success in comparing imaging modalities for tumor diagnosis, but this specific approach may provide novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with proven solid tumors or newly diagnosed mass strongly suspected to represent a solid tumor. * We might also include some patients with leukemia if there is concern for a focal lesion in any of their organs. * Participant's parents (if participant is under 18) or the participant (if participant is 18 years or older) must willingly give written informed consent prior to any image transfer to the image registry. Exclusion Criteria: * Patient has contraindications for MRI or PET/MR. This includes patients with cardiac pacemakers or intracranial vascular clips as well as patients with a blood glucose level \> 200 mg/dl. * Lack of parental permission (if participant is younger than 18) or lack of informed consent (if participant is at least 18 years of age). * Patient has a CNS primary tumor. * Pregnant women and fetuses
Where it's running
-
Stanford University, School of Medicine
Palo Alto, California, United States Recruiting
Study contacts
- Principal investigator: Heike Daldrup-Link, MD — Stanford University
- Study coordinator: Anne Muehe
- Email: amuehe@stanford.edu
- Phone: 650-720-8601
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.