Comparing ibuprofen arginine with and without physiotherapy for carpal tunnel syndrome
Pain Reduction Effect of a Combined Oral Ibuprofen Arginine and Neural Mobilization Treatment Versus an (Only) Oral Ibuprofen Arginine Treatment in Carpal Tunnel Syndrome
PHASE4 · Universidad Europea de Madrid · NCT06778759
This study is testing whether combining ibuprofen arginine with a specific physiotherapy technique can help reduce pain and improve function in people with carpal tunnel syndrome better than just using ibuprofen arginine alone.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 18 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Universidad Europea de Madrid (other) |
| Locations | 1 site (Valencia, Carabobo) |
| Trial ID | NCT06778759 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the pain reduction effects of a physiotherapy technique known as median nerve neural mobilization combined with ibuprofen arginine treatment against ibuprofen arginine treatment alone in patients diagnosed with carpal tunnel syndrome. Participants will be randomly assigned to one of two groups to evaluate the effectiveness of the combined approach versus the medication alone. The study will also assess the impact on the functionality of the affected upper limb. The trial is designed to provide insights into non-invasive treatment options for this condition.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with unilateral carpal tunnel syndrome who can understand Spanish and provide informed consent.
Not a fit: Patients with cognitive impairments, recent surgeries, or those on pain-reducing treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could offer a more effective treatment option for patients suffering from carpal tunnel syndrome.
How similar studies have performed: Other studies have shown promising results with similar non-invasive approaches, suggesting potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants must be medically diagnosed with unilateral carpal tunnel syndrome (with confirmative electrodiagnostic findings). * Full understanding of written and spoken Spanish (language). * Participants must freely consent to participate. * The presence of positive Phalen an Tinel sings. * The presence of carpal tunnel syndrome signs and symptoms Exclusion Criteria: * The lack to meet inclusion criterions, the presence of cognitive impairment, tumors, cancer, recent (affected) upper limb surgery or trauma, pregnancy, kinesiophobia, deformities of the (affected) upper limb, recent skin injuries or infections (in the affected upper limb), autoimmune inflammatory conditions or flu type symptoms, allergy to gabapentin, allergy to ibuprofen arginine, and also: participants must not be (during the present investigation) under any type of pain reducing treatment (conservative, homeopathic, invasive or not invasive)
Where this trial is running
Valencia, Carabobo
- Ciudad Hospitalaria Enrique Tejera — Valencia, Carabobo, Venezuela (RECRUITING)
Study contacts
- Principal investigator: Francisco Unda, PhD
- Study coordinator: Francisco Unda, PhD
- Email: 5299559@gmail.com
- Phone: 695634680
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Carpal Tunnel Syndrome, Ibuprofen arginine, Median nerve neural mobilization, Pain