Comparing hydromorphone and sufentanil for pain relief during labor
Official title: Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia: a Randomized Controlled Trial
Run by Maternal and Child Health Hospital of Hubei Province · NCT06036797 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether hydromorphone works better than sufentanil for pain relief during labor when used with a common numbing medication.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Ages | 20 Years to 40 Years |
| Sex | Women only |
| Enrollment | 240 (estimated) |
| Sponsor | Maternal and Child Health Hospital of Hubei Province Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT06036797 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include pregnant women with a single fetus who are classified as ASA physical status II and can provide informed consent.
✕Probably not a fit
Patients with severe respiratory or circulatory diseases, or those with placenta previa, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the efficacy and safety of hydromorphone combined with ropivacaine compared to sufentanil combined with ropivacaine for epidural labor analgesia. Participants will be randomly assigned to four groups, receiving different doses of hydromorphone or sufentanil alongside a consistent dose of ropivacaine. The goal is to determine if hydromorphone offers advantages in pain relief during labor and to identify the optimal dose for effective analgesia.
Why it matters
Potential benefit: If successful, this study could provide improved pain management options for women during labor.
How similar studies have gone: Other studies have explored similar analgesic combinations, but the specific comparison of hydromorphone and sufentanil in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status II * a single fetus * competent to provide informed consent Exclusion Criteria: * severe respiratory diseases including hypoxemia, respiratory failure and severe pneumonia * severe circulatory diseases including acute decompensated heart failure and peripartum cardiomyopathy * placenta previa
Where it's running
-
Maternal and Child Health Hospital of Hubei Province
Wuhan, Hubei, China Recruiting
Study contacts
- Principal investigator: Na Li, MD — Maternal and Child Health Hospital of Hubei Province
- Study coordinator: Na Li, MD
- Email: lina@hbfy.com
- Phone: +862763490107
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.