Comparing high flow nasal oxygen to endotracheal intubation during laryngeal surgery
Comparison of High Flow Nasal Oxygenation Versus Endotracheal Intubation on Recovery Profiles in Laryngeal Microsurgery
This study tests if using high flow nasal oxygen can help patients recover with less coughing after laryngeal surgery compared to the usual method of putting a tube in their throat.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 52 (estimated) |
| Ages | 19 Years to 80 Years |
| Sex | All |
| Sponsor | Ajou University School of Medicine Academic / other |
| Locations | 1 site (Suwon, Gyeongki-do) |
| Trial ID | NCT05559502 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of high flow nasal oxygenation (HFNO) versus endotracheal intubation (ET) on recovery profiles in patients undergoing laryngeal microsurgery. It aims to determine if HFNO can reduce coughing during emergence from anesthesia compared to traditional ET methods. The study involves administering total intravenous anesthesia (TIVA) with propofol and remifentanil while monitoring postoperative outcomes such as cough and sore throat. The hypothesis is that HFNO will provide a safer and more effective alternative to ET in this surgical context.
Who should consider this trial
Good fit: Ideal candidates are patients classified as American Society of Anesthesiologists 1 or 2 who require general anesthesia for laryngeal microsurgery.
Not a fit: Patients with major cardiovascular, pulmonary, or cerebrovascular diseases, as well as those undergoing laser laryngeal surgery or with morbid obesity, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved recovery experiences and reduced complications for patients undergoing laryngeal microsurgery.
How similar studies have performed: While the use of HFNO in various surgical contexts has shown promise, this specific comparison in laryngeal microsurgery is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with American Society of Anesthesiologists classification 1 or 2 who receive general anesthesia for laryngeal microsurgery Exclusion Criteria: * Patients with major cardiovascular, pulmonary, and cerebrovascular disease * Laser laryngeal surgery * Morbid obesity (BMI\>35 kg/m2)
Where this trial is running
Suwon, Gyeongki-do
- Ajou University Hospital — Suwon, Gyeongki-do, Korea, Republic of (Recruiting)
Study contacts
- Principal investigator: JongYeop Kim, M.D.,Ph.D. — Ajou University School of Medicine
- Study coordinator: TaeKwang Kim, M.D.
- Email: tk.kim@aumc.ac.kr
- Phone: 82-031-219-5589
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.