Comparing high and low power laser treatments for enlarged prostates
Comparative Study Between Safety and Efficacy of High Versus Low Power HOLEP in Enucleation of the Prostate; Prospective Randomized Double Blind Trial
This study is testing whether using high-power or low-power lasers for prostate surgery helps men with enlarged prostates feel better and have fewer side effects.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 45 Years and up |
| Sex | Male |
| Sponsor | Al-Azhar University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05678452 on ClinicalTrials.gov |
What this trial studies
This study evaluates the safety and effectiveness of high-power versus low-power Holmium laser enucleation of the prostate (HOLEP) in patients with benign prostatic hyperplasia (BPH). It aims to determine which method offers better enucleation efficiency while minimizing costs and reducing postoperative complications such as dysuria and negative sexual effects. The trial will involve patients with large prostates who are indicated for surgical intervention, comparing outcomes between the two laser power settings.
Who should consider this trial
Good fit: Ideal candidates for this study are men with large prostates who require surgical intervention for benign prostatic hyperplasia.
Not a fit: Patients with prostate cancer, recurrent adenomas, or neurological conditions affecting bladder function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective and cost-efficient treatment options for patients with enlarged prostates.
How similar studies have performed: While HOLEP is a widely used technique, this specific comparison of high versus low power settings is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * large prostate indicated for surgical intervention. Exclusion Criteria: * prostate cancer * recurrent adenomas * associated neurologic factors that may affect outcomes (e.g., neurogenic bladder)
Where this trial is running
Cairo
- Urology department - AlAzhar university — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohamed F Salman, MD
- Email: prof_mohamed_fawzy@yahoo.com
- Phone: +201111788996
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.