Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing hemodynamic assessments during rest and exercise for congenital heart disease

Official title: Invasive Hemodynamic Cardiopulmonary Exercise Testing for Assessment of Patients With Congenital Heart Disease (Cath CHD)

Run by Mayo Clinic · NCT06566196 · Data updated 2026-11-12

This study is trying to see if checking blood flow problems in people with congenital heart disease is more effective when they are resting compared to when they are exercising.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Rochester, Minnesota)
StatusRecruiting
StartedFebruary 10, 2025
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedMarch 5, 2026
Trial IDNCT06566196 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with congenital heart disease who are scheduled for clinically indicated cardiac catheterization.

Probably not a fit

Patients who are unable to provide consent or are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the differences in detecting hemodynamic abnormalities in patients with congenital heart disease by comparing invasive assessments conducted at rest versus during exercise. It will also assess the correlation between invasive and noninvasive hemodynamic indices derived from Doppler measurements. The study seeks to understand how disease severity relates to hemodynamic abnormalities identified in both conditions, potentially leading to improved diagnostic approaches.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of diagnosing hemodynamic issues in patients with congenital heart disease, leading to better-targeted treatments.

How similar studies have gone: While this approach is innovative, similar studies have shown promise in improving diagnostic accuracy for cardiovascular conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Congenital Heart Disease Diagnosis
* Undergoing Clinically indicated Cardiac Cath

Exclusion Criteria:

* Unable to consent
* Pregnancy

Where it's running

  • Mayo Clinic
    Rochester, Minnesota, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.