Comparing hemodynamic assessments during rest and exercise for congenital heart disease
Official title: Invasive Hemodynamic Cardiopulmonary Exercise Testing for Assessment of Patients With Congenital Heart Disease (Cath CHD)
Run by Mayo Clinic · NCT06566196 · Data updated 2026-11-12
This study is trying to see if checking blood flow problems in people with congenital heart disease is more effective when they are resting compared to when they are exercising.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Status | Recruiting |
| Started | February 10, 2025 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | March 5, 2026 |
| Trial ID | NCT06566196 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with congenital heart disease who are scheduled for clinically indicated cardiac catheterization.
✕Probably not a fit
Patients who are unable to provide consent or are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the differences in detecting hemodynamic abnormalities in patients with congenital heart disease by comparing invasive assessments conducted at rest versus during exercise. It will also assess the correlation between invasive and noninvasive hemodynamic indices derived from Doppler measurements. The study seeks to understand how disease severity relates to hemodynamic abnormalities identified in both conditions, potentially leading to improved diagnostic approaches.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of diagnosing hemodynamic issues in patients with congenital heart disease, leading to better-targeted treatments.
How similar studies have gone: While this approach is innovative, similar studies have shown promise in improving diagnostic accuracy for cardiovascular conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Congenital Heart Disease Diagnosis * Undergoing Clinically indicated Cardiac Cath Exclusion Criteria: * Unable to consent * Pregnancy
Where it's running
-
Mayo Clinic
Rochester, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Alexander Egbe, M.B.B.S., M.P.H. — Mayo Clinic
- Study coordinator: ACHD Research Program
- Email: RSTACHDRESPRG@mayo.edu
- Phone: 507-293-2565
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Adapting and testing PEN-Plus in Zambian primary care
Aiming to see if the PEN-Plus package can be adapted and used in two Zambian hospitals to better manage chronic diseases like heart disease, diabetes, hypertension, and sickle cell in primary care.
-
Wireless NIRS Sensor Use in the NICU for Monitoring on Neonates
A wireless NIRS sensor is tested on infants in the NICU to see how well it stays on and how it notes brain signals when used alongside standard wired sensors.
-
Screening for lipid disorders in children and teens with chronic diseases to flag cardiovascular risk
This study tests a blood test and a questionnaire to screen children and teens with chronic conditions for lipid metabolism disorders and familial hyperlipidemia.
-
Prehabilitation before heart surgery for adults with congenital heart disease
This study is testing whether a tailored, supervised exercise program before heart surgery helps adults with congenital heart disease perform better and improve fitness.
-
Accessible care model comparing nurse-led versus physician-led transition education for teens and young adults with congenital heart disease
This project will test whether an accessible care model and nurse-led versus physician-led transition education helps teens and young adults (ages 12–26) with congenital heart disease move successfully from pediatric to adult heart care.
-
Surgical techniques and outcomes across the lifespan in congenital heart disease in China
See which surgical factors and care patterns affect recovery after heart surgery for people with complex congenital heart disease in China.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.