Comparing hemodynamic assessments during rest and exercise for congenital heart disease
Invasive Hemodynamic Cardiopulmonary Exercise Testing for Assessment of Patients With Congenital Heart Disease (Cath CHD)
This study is trying to see if checking blood flow problems in people with congenital heart disease is more effective when they are resting compared to when they are exercising.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06566196 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the differences in detecting hemodynamic abnormalities in patients with congenital heart disease by comparing invasive assessments conducted at rest versus during exercise. It will also assess the correlation between invasive and noninvasive hemodynamic indices derived from Doppler measurements. The study seeks to understand how disease severity relates to hemodynamic abnormalities identified in both conditions, potentially leading to improved diagnostic approaches.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with congenital heart disease who are scheduled for clinically indicated cardiac catheterization.
Not a fit: Patients who are unable to provide consent or are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of diagnosing hemodynamic issues in patients with congenital heart disease, leading to better-targeted treatments.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving diagnostic accuracy for cardiovascular conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Congenital Heart Disease Diagnosis * Undergoing Clinically indicated Cardiac Cath Exclusion Criteria: * Unable to consent * Pregnancy
Where this trial is running
Rochester, Minnesota
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Alexander Egbe, M.B.B.S., M.P.H. — Mayo Clinic
- Study coordinator: ACHD Research Program
- Email: RSTACHDRESPRG@mayo.edu
- Phone: 507-293-2565
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.