Comparing fingerprick and venous blood for monitoring tacrolimus levels in kidney transplant patients
Developing an LC-MS/MS Method for Measurement of Tacrolimus and Creatinine Concentration From Finger-prick Blood Collected Using the Mitra Device
This study is testing whether fingerprick blood samples can effectively monitor tacrolimus levels in kidney transplant patients, making it easier for them to manage their treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Sex | All |
| Sponsor | Nottingham University Hospitals NHS Trust Academic / other |
| Locations | 1 site (Nottingham) |
| Trial ID | NCT06585293 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the effectiveness of fingerprick blood samples versus traditional venous blood samples for monitoring tacrolimus levels in kidney transplant patients. Tacrolimus is an essential immunosuppressant medication that requires careful dosage monitoring to prevent organ rejection and complications. The study will involve patients attending the renal clinic at Nottingham University Hospitals NHS Trust who are currently receiving tacrolimus treatment. Blood samples will be analyzed to determine if the fingerprick method can provide comparable results to the venous method, potentially improving patient convenience and reducing the need for hospital visits.
Who should consider this trial
Good fit: Ideal candidates for this study are kidney transplant patients receiving tacrolimus who require regular monitoring of their medication levels.
Not a fit: Patients who are not receiving tacrolimus or those who do not require regular monitoring of immunosuppressant levels may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more convenient and less invasive method for monitoring tacrolimus levels in kidney transplant patients.
How similar studies have performed: While the specific approach of using fingerprick samples for tacrolimus monitoring may be novel, similar studies have shown success in using alternative blood sampling methods for other medications.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients attending renal clinic who are receiving immunosuppressant treatment (tacrolimus) and require regular monitoring. Exclusion Criteria: * No exclusion criteria
Where this trial is running
Nottingham
- Nottingham University Hospitals NHS Trust — Nottingham, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Donna M Fullerton, PhD, FRCPath — Nottingham University Hospitals NHS Trust
- Study coordinator: Alison Lloyd
- Email: researchsponsor@nuh.nhs.uk
- Phone: 0115 924 9924
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.