Comparing fiberoptic and direct laryngoscopy for safer anesthesia induction
Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Induction
NA · American University of Beirut Medical Center · NCT06487988
This study tests whether using a fiberoptic method for putting people to sleep for surgery leads to better heart and blood pressure stability compared to the standard direct method.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Sponsor | American University of Beirut Medical Center (other) |
| Locations | 1 site (Beirut) |
| Trial ID | NCT06487988 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the hemodynamic stability, specifically blood pressure and heart rate, during intubation using either fiberoptic or direct oral methods with opioid-free anesthesia. It will involve 90 adults aged 18 to 55 years who are scheduled for elective surgeries under general anesthesia. Participants will be randomly assigned to one of the two intubation techniques, and the study will also assess the time taken for intubation and the occurrence of postoperative complications such as sore throat and hoarseness. The goal is to determine if fiberoptic intubation results in less hemodynamic instability compared to direct laryngoscopy.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 55 years, classified as ASA physical status I or II, and scheduled for elective surgery under general anesthesia.
Not a fit: Patients with a history of cardiovascular or lung diseases, hypertension, or those with predicted difficult airways may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to safer anesthesia practices with reduced cardiovascular risks during intubation.
How similar studies have performed: Limited studies have compared hemodynamic stability between fiberoptic and direct intubation in opioid-free anesthesia, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA (American Society of Anesthesiologists) physical status I and II * Range age of 18-55 years' old * Scheduled for elective surgery under general anesthesia. Exclusion Criteria: * History of cardiovascular diseases. * History of lung disease. * Hypertensive patient (BP\> 140/90) * Patient taking medications that affect blood pressure and heart rate * Morbid obesity (BMI \>30) * Severe GERD * Predicted difficult airway (Short TMD \<6 cm, Upper li bite test grade III, Mallampati score \>III) * Neck instability * Patient planned to receive rapid sequence intubation * Patient refusal to participate * History of difficult intubation/ ventilation
Where this trial is running
Beirut
- Christian Rouphael — Beirut, Lebanon (RECRUITING)
Study contacts
- Principal investigator: Christian Rouphael, MD — American University of Beirut Medical Center
- Study coordinator: Christian Rouphael, MD
- Email: cr30@aub.edu.lb
- Phone: 01 350 000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Analgesics, Opioid, Anesthesia, General, Heart Rate, Blood Pressure