Comparing femoral nerve block and IV analgesia for hip fracture pain management

Comparison of the Efficiency of Femur Nerve Block and Analgesia Treatment in Hip Fracture Patients in Emergency Department

Phase 4 Interventional Marmara University · NCT06862154

This study tests whether a femoral nerve block or IV pain medication works better for managing pain in older patients with hip fractures.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment119 (estimated)
Ages18 Years and up
SexAll
SponsorMarmara University Academic / other
Locations1 site (İstanbul, Pendik)
Trial IDNCT06862154 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of femoral nerve blocks versus intravenous analgesia in managing pain for patients with hip fractures. It aims to determine which method provides better pain control, enhances patient satisfaction, and supports quicker recovery. The study involves administering either fentanyl or a femoral nerve block to eligible patients and monitoring their pain levels and recovery outcomes. The trial is particularly focused on elderly patients who are at high risk for complications following hip fractures.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with a confirmed proximal femur fracture who can provide informed consent.

Not a fit: Patients with hemodynamic instability, severe trauma, or known allergies to the study medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for hip fracture patients, enhancing their recovery and quality of life.

How similar studies have performed: Previous studies have shown that peripheral nerve blocks can provide superior pain relief compared to systemic analgesia, indicating a promising approach in this area.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥18 years
* Radiologically confirmed proximal femur fracture (femoral neck or intertrochanteric fracture)
* Ability to provide informed consent or have a legal representative provide consent

Exclusion Criteria:

* Hemodynamic instability (SBP \<90 mmHg, HR \>120 bpm)
* Severe trauma requiring immediate surgical intervention (e.g., multiple trauma, head injury)
* Bleeding disorders or anticoagulation therapy (INR ≥2.5, platelet count \<50,000/mm³)
* Known allergy to local anesthetics (bupivacaine) or opioids (fentanyl)
* Pregnancy
* Prior administration of local anesthetic blocks or systemic opioids before arrival
* Periprosthetic fractures or previous surgery on the affected hip

Where this trial is running

İstanbul, Pendik

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hip FracturesAnalgesiaFemoral NerveUltrasound guided analgesiapain control
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.