Comparing FAPI and FDG PET Imaging in Cancer Patients
Official title: Application of FAPI and FDG PET Imaging in Patients With Different Types of Cancer
Run by Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · NCT06284070 · Data updated 2026-11-12
This study is testing if a new type of cancer imaging called FAPI is better than the usual FDG PET scan for helping doctors find and diagnose different kinds of cancer in adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing Municipality) |
| Status | Recruiting |
| Started | January 1, 2024 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | February 28, 2024 |
| Trial ID | NCT06284070 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older with suspected or newly diagnosed malignant tumors.
✕Probably not a fit
Patients who are pregnant or have conditions that prevent them from undergoing imaging will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the effectiveness of fibroblast activation protein inhibitors (FAPI) compared to traditional 18F-FDG PET imaging in diagnosing various types of cancer. It will involve adult patients with suspected or newly diagnosed malignant tumors who will undergo both imaging techniques within a week. Clinical data, including tumor markers and imaging results, will be collected and analyzed to assess the performance of these imaging modalities in identifying primary and metastatic lesions. The study is set to run from January 2024 to December 2029.
Why it matters
Potential benefit: If successful, this study could provide a more accurate imaging alternative for cancer diagnosis, potentially improving patient outcomes.
How similar studies have gone: While the use of FAPI in imaging is emerging, this specific comparative approach has not been widely tested, making it a novel investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adult patients (≥ 18 years old); 2. Suspected or newly diagnosed malignant tumor patients; 3. Patients who underwent 18F-FDG and 18F-FAPI PET scans within one week; 4. Patients who are able to provide informed consent forms (signed by participants, parents, or legal representatives) and consent forms in accordance with the guidelines of the Clinical Research Ethics Committee. Exclusion Criteria: 1. Pregnant women; 2. Scanned images with poor image quality due to factors such as body movement; 3. Patients with mental illness or other unsuitable conditions for examination, poor compliance, etc.
Where it's running
-
Department of Nuclear Medicine, Daping Hospital of Army Medical University
Chongqing, Chongqing Municipality, China Recruiting
Study contacts
- Study coordinator: Xiao Chen, Ph.D
- Email: xiaochen229@foxmail.com
- Phone: 15922970174
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.