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Clinical trial Recruiting at 1 site Interventional Ages 12 to 17

Comparing family-based and adolescent-only approaches to substance use intervention

Official title: Adolescent-Only SBI Versus Family-Based SBI in Primary Care for Adolescent Alcohol Use

Run by The National Center on Addiction and Substance Abuse at Columbia University · NCT05964010 · Data updated 2026-11-12

This study is testing whether involving families in substance use treatment helps teenagers aged 12-17 do better than just using a standard approach that focuses only on the teens.

Quick facts

Study typeInterventional
Ages12 Years to 17 Years
SexAll
Enrollment2300 (estimated)
SponsorThe National Center on Addiction and Substance Abuse at Columbia University
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedMarch 1, 2024
Main results expectedNovember 2028
Study endsDecember 2029
Registry record updatedMarch 18, 2026
Trial IDNCT05964010 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adolescents aged 12-17 who attend a primary care appointment with a caregiver and are fluent in English or Spanish.

Probably not a fit

Patients who do not have a caregiver present during the appointment or are not fluent in English or Spanish may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of a family-based approach versus a standard adolescent-only approach for screening, brief intervention, and referral to treatment for substance use in adolescents aged 12-17. The study involves 2,300 adolescents and their caregivers attending pediatric primary care visits in urban settings. Participants will undergo assessments at multiple follow-up points to measure outcomes related to substance use, behavioral problems, and quality of life. The interventions are delivered primarily through digital platforms during the initial visit.

Why it matters

Potential benefit: If successful, this study could enhance the effectiveness of substance use interventions by involving caregivers, potentially leading to better outcomes for adolescents.

How similar studies have gone: Other studies have shown success with family-based approaches in substance use interventions, indicating potential for positive outcomes in this trial.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Youth aged 12-17 years with a primary caregiver (i.e., parental figure) also in attendance to primary care appointment
* Youth and caregiver are fluent in English or Spanish
* Youth and caregiver are capable of using audio-assisted informed consent procedures and independently operating a hand-held tablet device
* Youth and caregiver are complete routine site AOD risk screening questions prompted during PC visit intake

Where it's running

  • Columbia University Medical Center
    New York, New York, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Substance Use 565The National Center on Addiction and Substance Abuse at Columbia University 4
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.