Comparing eye pressure measurements using the TonoVera device and other tonometers

Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices

Not applicable Interventional State University of New York at Buffalo · NCT05523622

This study is testing how well the TonoVera device measures eye pressure compared to other common devices to help people with glaucoma.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment300 (estimated)
SexAll
SponsorState University of New York at Buffalo Academic / other
Locations1 site (Buffalo, New York)
Trial IDNCT05523622 on ClinicalTrials.gov

What this trial studies

This study evaluates the accuracy of the TonoVera tonometer by comparing its intraocular pressure (IOP) measurements with those obtained from the Goldmann Applanation Tonometry and iCare devices. Participants will undergo multiple IOP measurements using each device on both eyes, along with assessments of central corneal thickness and corneal hysteresis. The goal is to determine how well the TonoVera performs relative to established methods in measuring eye pressure, which is crucial for glaucoma management.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 99 who are in good general health and can provide informed consent.

Not a fit: Patients with conditions that prevent accurate tonometry readings, such as significant corneal pathology or those unable to comply with study procedures, may not benefit.

Why it matters

Potential benefit: If successful, this study could lead to improved accuracy in measuring intraocular pressure, enhancing glaucoma diagnosis and management.

How similar studies have performed: Other studies have successfully compared tonometry devices, but the TonoVera is a novel device being evaluated in this context.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ability to provide signed and dated informed consent form. Patients willing to comply with all study procedures and be available for the duration of the study.

Male or female patients aged 18 to 99 Patients in good general health as evidenced by ability to come to their appointment on day of study.

Exclusion Criteria:

* Patients age less than 18 years Patients unable or unwilling to provide informed consent to participate in the study Patients for which an accurate tonometry reading cannot be performed. This may include those with blepharospasm (lid squeezers), nystagmus, extensive corneal pathology, or contact lens wearers who cannot remove their contact lens.Patients with significant scleral thinning Patients with a known allergy to proparacaine or fluorescein as these are used to anesthetize and allow measurement respectively of the eye when used with the Goldmann tonometer.

Where this trial is running

Buffalo, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Glaucoma
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.