Comparing ESPB and SPSIPB nerve blocks for pain after VATS
Official title: Comparison of the Effects of Ultrasound-Guided Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block on Postoperative Analgesia Management in Patients Undergoing Video-Assisted Thoracoscopic Surgery
Run by Bursa City Hospital · NCT07232940 · Data updated 2026-11-12
This trial will test whether the serratus posterior superior intercostal plane block (SPSIPB) or the erector spinae plane block (ESPB) gives better pain relief and satisfaction for adults having VATS.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Bursa City Hospital Government |
| Locations | 1 site (Bursa, Nilüfer) |
| Status | Recruiting |
| Started | November 15, 2025 |
| Main results expected | May 15, 2026 |
| Study ends | May 15, 2026 |
| Registry record updated | December 16, 2025 |
| Trial ID | NCT07232940 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 with ASA physical status I–III scheduled for elective VATS who do not have contraindications to regional nerve blocks are ideal candidates.
✕Probably not a fit
Patients with coagulopathy, local infection at the injection site, known local anesthetic allergy, current chronic opioid therapy, uncontrolled systemic disease, or pregnancy are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Video-assisted thoracoscopic surgery (VATS) causes significant postoperative pain despite small incisions, and effective regional analgesia is important to reduce acute and chronic pain. Current PROSPECT guidance supports ESPB or paravertebral block for VATS, while the serratus posterior superior intercostal plane block (SPSIPB) is a recently described technique that may cover C3–T10 dermatomes. This study will compare postoperative analgesic efficacy and patient satisfaction between ESPB and SPSIPB in adult elective VATS patients treated at Bursa City Hospital. Typical inclusion criteria are adults 18–65 years with ASA I–III, with exclusions for coagulopathy, local anesthetic allergy, chronic opioid use, uncontrolled major comorbidities, infection at the injection site, and pregnancy or breastfeeding.
Why it matters
Potential benefit: If one block provides better and longer pain relief with fewer opioid needs, patients could experience less acute pain, lower opioid use, and potentially lower risk of chronic postoperative pain after VATS.
How similar studies have gone: ESPB and paravertebral blocks have prior supportive data for VATS analgesia, whereas SPSIPB is a newly described technique with limited comparative evidence to date.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18-65 years with ASA physical status I-III who will undergo elective video-assisted thoracoscopic surgery (VATS) will be included. Exclusion Criteria: * Patients who do not consent to participate in the study Patients with coagulopathy Patients with a history of local anesthetic allergy or toxicity Patients with hepatic or renal failure Patients with uncontrolled diabetes Patients with uncontrolled hypertension Mentally disabled patients Patients receiving chronic pain treatment (opioid users) Patients using antidepressant medication Patients with neuropathic pain Mentally disabled patients Presence of infection at the injection site Pregnant or breastfeeding women, or those with suspected pregnancy
Where it's running
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Bursa City Hospital
Bursa, Nilüfer, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Eralp Çevikkalp
- Email: eralpcevikkalp@hotmail.com
- Phone: +905054554875
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Rhomboid Intercostal Block vs Serratus Posterior Superior Intercostal Plane Block for VATS Pain
This study tests two regional anesthesia techniques to see which better reduces postoperative pain after video-assisted thoracic surgery in adults undergoing thoracic procedures.
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Pre-incisional ropivacaine plus diprospan to relieve pain after VATS
This study tests whether injecting ropivacaine with diprospan before surgery can reduce postoperative pain for adults and children undergoing VATS lung surgery.
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Infiltration with ropivacaine plus triamcinolone to relieve pain after VATS surgery
This study tests whether injecting ropivacaine with or without triamcinolone before incision can reduce pain after thoracoscopic lung surgery in adults.
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Erector spinae plane block versus thoracoscopic intercostal nerve block for pain after VATS lung surgery
This compares two nerve-block techniques to see which gives better pain control after elective VATS lung surgery in adults.
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Liposomal bupivacaine for rhomboid intercostal nerve block to reduce pain after VATS
We will test whether adding long‑acting liposomal bupivacaine to a rhomboid intercostal nerve block reduces pain after video‑assisted thoracoscopic lung surgery in adults.
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Liposomal bupivacaine to reduce pain after VATS
This test will see if a long‑acting liposomal bupivacaine injection at the incision eases postoperative pain for adults having VATS lung surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.