Comparing electrosurgical techniques for treating achalasia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness and safety of two electrosurgical modes, Spray Coagulation and Precisect mode, during the Peroral Endoscopic Esophageal Myotomy (POEM) procedure for patients with achalasia. The study aims to determine which mode provides better outcomes in terms of tissue damage and coagulation efficiency. Participants will undergo high-resolution manometry and gastroscopy to confirm their esophageal motility disorder before being assigned to one of the two intervention groups.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing POEM procedure for any esophageal motility disorder
* Esophageal motility disorder confirmed by high-resolution manometry and gastroscopy

Exclusion Criteria:

* Esophageal varices
* Esophageal neoplasms
* Non-correctable coagulopathy
* Failure to provide an informed consent

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Principal investigator: hany shehab — Cairo University
• Study coordinator: hany Shehab, MD, FRCP
• Email: h.shehab@kasralainy.edu.eg
• Phone: +201111111071

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Full-thickness vs progressive myotomy in POEM for achalasia

  This trial tests whether a full-thickness myotomy during POEM works better than a partial, progressive approach for people with achalasia, to see which method better relieves symptoms with fewer side effects.

  Recruiting at 2 sites Phase 2 Cairo University · Cairo and 1 other locations · NCT07875686

• Impact of Patient Position on EndoFLIP Measurements in Kids and Young Adults

  This study tests whether EndoFLIP measurements differ when patients are in the supine versus left-side position during the procedure.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07780981

• A registry for adults with esophageal movement and reflux problems.

  This project will collect esophageal function tests (manometry, pH-impedance, FLIP) and clinical data from adults with reflux or swallowing symptoms to see if combining these results helps guide diagnosis and long-term care.

  Recruiting IRCCS San Raffaele · Milan, Lombardy · NCT07506746

• Speedboat UltraSlim™ for POEM in adults with achalasia and other esophageal motility disorders.

  This registry will see if using the Speedboat UltraSlim™ device for POEM is safe and effective for adults with achalasia or other esophageal motility disorders.

  Recruiting Baylor College of Medicine · Houston, Texas · NCT07496840

• Using the SpydrBlade Flex device during POEM for achalasia and EGJ outflow obstruction

  This will test whether using the SpydrBlade Flex device during POEM is safe and effective for adults with achalasia or EGJ outflow obstruction.

  Recruiting at 2 sites Chinese University of Hong Kong · Guayaquil and 1 other locations · NCT07406945

• Indocyanine green fluorescence during laparoscopic Heller–Dor for achalasia

  This study will try using indocyanine green dye during laparoscopic Heller‑Dor in adults with type I or II achalasia to find mucosal leaks during surgery and help guide repairs.

  Recruiting Federico II University · Naples · NCT07181070

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.