Comparing effects of different PEEP levels during laparoscopic surgery
Comparison of the Effects of Different Positive Expiratory Pressure Levels on Patient Oxygenation and Mechanical Power Values in Laparoscopic Surgeries
This study is testing whether using different levels of breathing support during laparoscopic surgery can help protect the lungs and reduce complications.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 84 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Kocaeli City Hospital Government |
| Locations | 1 site (Kocaeli, Izmıt) |
| Trial ID | NCT06625099 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the effects of standard and optimum positive end-expiratory pressures (PEEP) on mechanical power during laparoscopic surgeries. It addresses the challenges of perioperative pulmonary complications and ventilator-associated lung injury by evaluating lung protective ventilation strategies. The study will analyze how varying PEEP levels impact lung mechanics and potential complications such as atelectasis and barotrauma. By utilizing a mechanical power formula, the study seeks to simplify the assessment of lung ventilation dynamics.
Who should consider this trial
Good fit: Ideal candidates are ASA class 1-2 patients undergoing laparoscopic abdominal surgery without known lung or coronary artery diseases.
Not a fit: Patients with intraoperative complications, neurological diseases, or those who are not extubated postoperatively may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved ventilation strategies that minimize lung injury during laparoscopic surgeries.
How similar studies have performed: Other studies have suggested the benefits of lung protective ventilation strategies, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * within the appropriate age range * agreeing to participate in the study * again receiving lancetesthesia * volume controlled ventilation * no known lung disease * no known coronary artery disease * ASA class 1-2 patients Exclusion Criteria: * . Patients who do not want to be included in the study will not be included * Patients with intraoperative deep hypotension (mean arterial pressure \<50) will be excluded. * Those who develop intraoperative hypothermia or have other anesthesia complications will be excluded. * Patients who will not be extubated postoperatively will be excluded from the study. * Those with neurological diseases or those using psychiatric medications will also be excluded from the study.
Where this trial is running
Kocaeli, Izmıt
- Kocaeli City Hospital — Kocaeli, Izmıt, Turkey (Recruiting)
Study contacts
- Study coordinator: Esra Turk, Md
- Email: esraa.tuurk@gmail.com
- Phone: +905057531975
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.